Sommers JA - Search Results

1

Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors.

Banerjee T, Aggarwal M, Sommers JA, Brosh RM Jr. Banerjee T, et al. Among authors: sommers ja. Methods. 2016 Oct 1;108:130-41. doi: 10.1016/j.ymeth.2016.04.007. Epub 2016 Apr 7. Methods. 2016. PMID: 27064001 Free PMC article. Review.

2

Werner syndrome protein: biochemical properties and functional interactions.

Bohr VA, Cooper M, Orren D, Machwe A, Piotrowski J, Sommers J, Karmakar P, Brosh R. Bohr VA, et al. Exp Gerontol. 2000 Sep;35(6-7):695-702. doi: 10.1016/s0531-5565(00)00145-5. Exp Gerontol. 2000. PMID: 11053659 Review.

3

p53 Modulates the exonuclease activity of Werner syndrome protein.

Brosh RM Jr, Karmakar P, Sommers JA, Yang Q, Wang XW, Spillare EA, Harris CC, Bohr VA. Brosh RM Jr, et al. Among authors: sommers ja. J Biol Chem. 2001 Sep 14;276(37):35093-102. doi: 10.1074/jbc.M103332200. Epub 2001 Jun 26. J Biol Chem. 2001. PMID: 11427532 Free article.

4

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.

Brosh RM Jr, von Kobbe C, Sommers JA, Karmakar P, Opresko PL, Piotrowski J, Dianova I, Dianov GL, Bohr VA. Brosh RM Jr, et al. Among authors: sommers ja. EMBO J. 2001 Oct 15;20(20):5791-801. doi: 10.1093/emboj/20.20.5791. EMBO J. 2001. PMID: 11598021 Free PMC article.

5

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.

Karmakar P, Piotrowski J, Brosh RM Jr, Sommers JA, Miller SP, Cheng WH, Snowden CM, Ramsden DA, Bohr VA. Karmakar P, et al. Among authors: sommers ja. J Biol Chem. 2002 May 24;277(21):18291-302. doi: 10.1074/jbc.M111523200. Epub 2002 Mar 11. J Biol Chem. 2002. PMID: 11889123 Free article.

6

Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase.

Brosh RM Jr, Waheed J, Sommers JA. Brosh RM Jr, et al. Among authors: sommers ja. J Biol Chem. 2002 Jun 28;277(26):23236-45. doi: 10.1074/jbc.M111446200. Epub 2002 Apr 15. J Biol Chem. 2002. PMID: 11956187 Free article.

7

Biochemical characterization of the WRN-FEN-1 functional interaction.

Brosh RM Jr, Driscoll HC, Dianov GL, Sommers JA. Brosh RM Jr, et al. Among authors: sommers ja. Biochemistry. 2002 Oct 8;41(40):12204-16. doi: 10.1021/bi026031j. Biochemistry. 2002. PMID: 12356323

8

The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein.

Sharma S, Sommers JA, Driscoll HC, Uzdilla L, Wilson TM, Brosh RM Jr. Sharma S, et al. Among authors: sommers ja. J Biol Chem. 2003 Jun 27;278(26):23487-96. doi: 10.1074/jbc.M212798200. Epub 2003 Apr 18. J Biol Chem. 2003. PMID: 12704184 Free article.

9

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.

Sharma S, Otterlei M, Sommers JA, Driscoll HC, Dianov GL, Kao HI, Bambara RA, Brosh RM Jr. Sharma S, et al. Among authors: sommers ja. Mol Biol Cell. 2004 Feb;15(2):734-50. doi: 10.1091/mbc.e03-08-0567. Epub 2003 Dec 2. Mol Biol Cell. 2004. PMID: 14657243 Free PMC article.

10

Stimulation of flap endonuclease-1 by the Bloom's syndrome protein.

Sharma S, Sommers JA, Wu L, Bohr VA, Hickson ID, Brosh RM Jr. Sharma S, et al. Among authors: sommers ja. J Biol Chem. 2004 Mar 12;279(11):9847-56. doi: 10.1074/jbc.M309898200. Epub 2003 Dec 19. J Biol Chem. 2004. PMID: 14688284 Free article.

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