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Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages.
Stadler M, Pudelko K, Biermeier A, Walterskirchen N, Gaigneaux A, Weindorfer C, Harrer N, Klett H, Hengstschläger M, Schüler J, Sommergruber W, Oehler R, Bergmann M, Letellier E, Dolznig H. Stadler M, et al. Among authors: sommergruber w. Cancer Lett. 2021 Nov 1;520:184-200. doi: 10.1016/j.canlet.2021.07.006. Epub 2021 Jul 10. Cancer Lett. 2021. PMID: 34256095 Free article.
High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.
Rudisch A, Dewhurst MR, Horga LG, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W. Rudisch A, et al. Among authors: sommergruber w. PLoS One. 2015 Apr 28;10(4):e0124283. doi: 10.1371/journal.pone.0124283. eCollection 2015. PLoS One. 2015. PMID: 25919140 Free PMC article.
Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer.
Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, Crncec I, Kramer N, Unger C, Hengstschläger M, Eferl R, Moriggl R, Sommergruber W, Gerner C, Dolznig H. Unterleuthner D, et al. Among authors: sommergruber w. Angiogenesis. 2020 May;23(2):159-177. doi: 10.1007/s10456-019-09688-8. Epub 2019 Oct 30. Angiogenesis. 2020. PMID: 31667643 Free PMC article.
Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.
Unger C, Kramer N, Unterleuthner D, Scherzer M, Burian A, Rudisch A, Stadler M, Schlederer M, Lenhardt D, Riedl A, Walter S, Wernitznig A, Kenner L, Hengstschläger M, Schüler J, Sommergruber W, Dolznig H. Unger C, et al. Among authors: sommergruber w. Oncogene. 2017 Sep 21;36(38):5341-5355. doi: 10.1038/onc.2017.116. Epub 2017 May 22. Oncogene. 2017. PMID: 28534511
Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.
Kramer N, Schmöllerl J, Unger C, Nivarthi H, Rudisch A, Unterleuthner D, Scherzer M, Riedl A, Artaker M, Crncec I, Lenhardt D, Schwarz T, Prieler B, Han X, Hengstschläger M, Schüler J, Eferl R, Moriggl R, Sommergruber W, Dolznig H. Kramer N, et al. Among authors: sommergruber w. Oncogene. 2017 Sep 28;36(39):5460-5472. doi: 10.1038/onc.2017.144. Epub 2017 May 29. Oncogene. 2017. PMID: 28553956
IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.
Rupp C, Scherzer M, Rudisch A, Unger C, Haslinger C, Schweifer N, Artaker M, Nivarthi H, Moriggl R, Hengstschläger M, Kerjaschki D, Sommergruber W, Dolznig H, Garin-Chesa P. Rupp C, et al. Among authors: sommergruber w. Oncogene. 2015 Feb 12;34(7):815-25. doi: 10.1038/onc.2014.18. Epub 2014 Mar 17. Oncogene. 2015. PMID: 24632618
3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment.
Rebelo SP, Pinto C, Martins TR, Harrer N, Estrada MF, Loza-Alvarez P, Cabeçadas J, Alves PM, Gualda EJ, Sommergruber W, Brito C. Rebelo SP, et al. Among authors: sommergruber w. Biomaterials. 2018 May;163:185-197. doi: 10.1016/j.biomaterials.2018.02.030. Epub 2018 Feb 13. Biomaterials. 2018. PMID: 29477032 Free article.
82 results