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Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
Künzel SR, Hoffmann M, Weber S, Künzel K, Kämmerer S, Günscht M, Klapproth E, Rausch JSE, Sadek MS, Kolanowski T, Meyer-Roxlau S, Piorkowski C, Tugtekin SM, Rose-John S, Yin X, Mayr M, Kuhlmann JD, Wimberger P, Grützmann K, Herzog N, Küpper JH, O'Reilly M, Kabir SN, Sommerfeld LC, Guan K, Wielockx B, Fabritz L, Nattel S, Ravens U, Dobrev D, Wagner M, El-Armouche A. Künzel SR, et al. Among authors: sommerfeld lc. Circ Res. 2021 Oct;129(8):804-820. doi: 10.1161/CIRCRESAHA.121.319425. Epub 2021 Aug 26. Circ Res. 2021. PMID: 34433292 Free PMC article.
High resolution optical mapping of cardiac electrophysiology in pre-clinical models.
O'Shea C, Winter J, Kabir SN, O'Reilly M, Wells SP, Baines O, Sommerfeld LC, Correia J, Lei M, Kirchhof P, Holmes AP, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: sommerfeld lc. Sci Data. 2022 Mar 31;9(1):135. doi: 10.1038/s41597-022-01253-1. Sci Data. 2022. PMID: 35361792 Free PMC article.
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.
O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Among authors: sommerfeld lc. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.
JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling.
Winters J, von Braunmuhl ME, Zeemering S, Gilbers M, Brink TT, Scaf B, Guasch E, Mont L, Batlle M, Sinner M, Hatem S, Mansour MK, Fabritz L, Sommerfeld LC, Kirchhof P, Isaacs A, Stoll M, Schotten U, Verheule S. Winters J, et al. Among authors: sommerfeld lc. Sci Rep. 2020 Nov 18;10(1):20074. doi: 10.1038/s41598-020-76932-3. Sci Rep. 2020. PMID: 33208780 Free PMC article.
An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions.
Chua W, Cardoso VR, Guasch E, Sinner MF, Al-Taie C, Brady P, Casadei B, Crijns HJGM, Dudink EAMP, Hatem SN, Kääb S, Kastner P, Mont L, Nehaj F, Purmah Y, Reyat JS, Schotten U, Sommerfeld LC, Zeemering S, Ziegler A, Gkoutos GV, Kirchhof P, Fabritz L. Chua W, et al. Among authors: sommerfeld lc. Sci Rep. 2023 Oct 5;13(1):16743. doi: 10.1038/s41598-023-42331-7. Sci Rep. 2023. PMID: 37798357 Free PMC article.
Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium.
Winters J, Isaacs A, Zeemering S, Kawczynski M, Maesen B, Maessen J, Bidar E, Boukens B, Hermans B, van Hunnik A, Casadei B, Fabritz L, Chua W, Sommerfeld L, Guasch E, Mont L, Batlle M, Hatem S, Kirchhof P, Wakili R, Sinner M, Stoll M, Goette A, Verheule S, Schotten U. Winters J, et al. J Am Heart Assoc. 2023 Nov 20;12(22):e031220. doi: 10.1161/JAHA.123.031220. Online ahead of print. J Am Heart Assoc. 2023. PMID: 37982389 Free PMC article.
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse.
Sommerfeld LC, Holmes AP, Yu TY, O'Shea C, Kavanagh DM, Pike JM, Wright T, Syeda F, Aljehani A, Kew T, Cardoso VR, Kabir SN, Hepburn C, Menon PR, Broadway-Stringer S, O'Reilly M, Witten A, Fortmueller L, Lutz S, Kulle A, Gkoutos GV, Pavlovic D, Arlt W, Lavery GG, Steeds R, Gehmlich K, Stoll M, Kirchhof P, Fabritz L. Sommerfeld LC, et al. J Physiol. 2024 Feb 12. doi: 10.1113/JP284597. Online ahead of print. J Physiol. 2024. PMID: 38345865
11 results