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Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
Yang SJ, Singh AK, Drow T, Tappen T, Honaker Y, Barahmand-Pour-Whitman F, Linsley PS, Cerosaletti K, Mauk K, Xiang Y, Smith J, Mortensen E, Cook PJ, Sommer K, Khan I, Liggitt D, Rawlings DJ, Buckner JH. Yang SJ, et al. Among authors: sommer k. Sci Transl Med. 2022 Oct 5;14(665):eabn1716. doi: 10.1126/scitranslmed.abn1716. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197963
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: sommer k. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.
Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ. Sather BD, et al. Among authors: sommer k. Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530. Sci Transl Med. 2015. PMID: 26424571 Free PMC article.
358 results