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ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H. Fougerat A, et al. Among authors: sommer c. Cell Rep. 2022 Jun 7;39(10):110910. doi: 10.1016/j.celrep.2022.110910. Cell Rep. 2022. PMID: 35675775 Free article.
The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression.
Fougeray T, Polizzi A, Régnier M, Fougerat A, Ellero-Simatos S, Lippi Y, Smati S, Lasserre F, Tramunt B, Huillet M, Dopavogui L, Salvi J, Nédélec E, Gigot V, Smith L, Naylies C, Sommer C, Haas JT, Wahli W, Duez H, Gourdy P, Gamet-Payrastre L, Benani A, Burnol AF, Loiseau N, Postic C, Montagner A, Guillou H. Fougeray T, et al. Among authors: sommer c. Cell Rep. 2022 Apr 12;39(2):110674. doi: 10.1016/j.celrep.2022.110674. Cell Rep. 2022. PMID: 35417722 Free article.
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: sommer c. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
Early life stress induces type 2 diabetes-like features in ageing mice.
Ilchmann-Diounou H, Olier M, Lencina C, Riba A, Barretto S, Nankap M, Sommer C, Guillou H, Ellero-Simatos S, Guzylack-Piriou L, Théodorou V, Ménard S. Ilchmann-Diounou H, et al. Among authors: sommer c. Brain Behav Immun. 2019 Aug;80:452-463. doi: 10.1016/j.bbi.2019.04.025. Epub 2019 Apr 11. Brain Behav Immun. 2019. PMID: 30981713
Early life stress in mice is a suitable model for Irritable Bowel Syndrome but does not predispose to colitis nor increase susceptibility to enteric infections.
Riba A, Olier M, Lacroix-Lamandé S, Lencina C, Bacquié V, Harkat C, Van Langendonck N, Gillet M, Cartier C, Baron M, Sommer C, Mallet V, Zill M, Robert H, Laurent F, Ellero-Simatos S, Théodorou V, Ménard S. Riba A, et al. Among authors: sommer c. Brain Behav Immun. 2018 Oct;73:403-415. doi: 10.1016/j.bbi.2018.05.024. Epub 2018 May 31. Brain Behav Immun. 2018. PMID: 29860025
Paneth Cell Defects Induce Microbiota Dysbiosis in Mice and Promote Visceral Hypersensitivity.
Riba A, Olier M, Lacroix-Lamandé S, Lencina C, Bacquié V, Harkat C, Gillet M, Baron M, Sommer C, Mallet V, Salvador-Cartier C, Laurent F, Théodorou V, Ménard S. Riba A, et al. Among authors: sommer c. Gastroenterology. 2017 Dec;153(6):1594-1606.e2. doi: 10.1053/j.gastro.2017.08.044. Epub 2017 Sep 1. Gastroenterology. 2017. PMID: 28865734
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.
Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. Vinnakota JM, et al. Among authors: sommer c. Nat Cancer. 2024 May 13. doi: 10.1038/s43018-024-00764-7. Online ahead of print. Nat Cancer. 2024. PMID: 38741011
1,284 results