Somlo S - Search Results

1

The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion.

Onuchic L, Padovano V, Schena G, Rajendran V, Dong K, Shi X, Pandya R, Rai V, Gresko NP, Ahmed O, Lam TT, Wang W, Shen H, Somlo S, Caplan MJ. Onuchic L, et al. Among authors: somlo s. Nat Commun. 2023 Mar 30;14(1):1790. doi: 10.1038/s41467-023-37449-1. Nat Commun. 2023. PMID: 36997516 Free PMC article.

2

The pathogenesis of autosomal dominant polycystic kidney disease: an update.

Somlo S, Markowitz GS. Somlo S, et al. Curr Opin Nephrol Hypertens. 2000 Jul;9(4):385-94. doi: 10.1097/00041552-200007000-00010. Curr Opin Nephrol Hypertens. 2000. PMID: 10926175 Review.

3

Vascular expression of polycystin-2.

Torres VE, Cai Y, Chen XI, Wu GQ, Geng L, Cleghorn KA, Johnson CM, Somlo S. Torres VE, et al. Among authors: somlo s. J Am Soc Nephrol. 2001 Jan;12(1):1-9. doi: 10.1681/ASN.V1211. J Am Soc Nephrol. 2001. PMID: 11134244

4

Polycystin-2 is an intracellular calcium release channel.

Koulen P, Cai Y, Geng L, Maeda Y, Nishimura S, Witzgall R, Ehrlich BE, Somlo S. Koulen P, et al. Among authors: somlo s. Nat Cell Biol. 2002 Mar;4(3):191-7. doi: 10.1038/ncb754. Nat Cell Biol. 2002. PMID: 11854751

5

Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease.

Wu G, Tian X, Nishimura S, Markowitz GS, D'Agati V, Park JH, Yao L, Li L, Geng L, Zhao H, Edelmann W, Somlo S. Wu G, et al. Among authors: somlo s. Hum Mol Genet. 2002 Aug 1;11(16):1845-54. doi: 10.1093/hmg/11.16.1845. Hum Mol Genet. 2002. PMID: 12140187

6

Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.

Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Grimm DH, et al. Among authors: somlo s. J Biol Chem. 2003 Sep 19;278(38):36786-93. doi: 10.1074/jbc.M306536200. Epub 2003 Jul 2. J Biol Chem. 2003. PMID: 12840011 Free article.

7

Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells.

Aguiari G, Banzi M, Gessi S, Cai Y, Zeggio E, Manzati E, Piva R, Lambertini E, Ferrari L, Peters DJ, Lanza F, Harris PC, Borea PA, Somlo S, Del Senno L. Aguiari G, et al. Among authors: somlo s. FASEB J. 2004 May;18(7):884-6. doi: 10.1096/fj.03-0687fje. Epub 2004 Mar 4. FASEB J. 2004. PMID: 15001556

8

The N-terminal extracellular domain is required for polycystin-1-dependent channel activity.

Babich V, Zeng WZ, Yeh BI, Ibraghimov-Beskrovnaya O, Cai Y, Somlo S, Huang CL. Babich V, et al. Among authors: somlo s. J Biol Chem. 2004 Jun 11;279(24):25582-9. doi: 10.1074/jbc.M402829200. Epub 2004 Apr 1. J Biol Chem. 2004. PMID: 15060061 Free article.

9

Mutations in SEC63 cause autosomal dominant polycystic liver disease.

Davila S, Furu L, Gharavi AG, Tian X, Onoe T, Qian Q, Li A, Cai Y, Kamath PS, King BF, Azurmendi PJ, Tahvanainen P, Kääriäinen H, Höckerstedt K, Devuyst O, Pirson Y, Martin RS, Lifton RP, Tahvanainen E, Torres VE, Somlo S. Davila S, et al. Among authors: somlo s. Nat Genet. 2004 Jun;36(6):575-7. doi: 10.1038/ng1357. Epub 2004 May 9. Nat Genet. 2004. PMID: 15133510

10

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.

Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. Chauvet V, et al. Among authors: somlo s. J Clin Invest. 2004 Nov;114(10):1433-43. doi: 10.1172/JCI21753. J Clin Invest. 2004. PMID: 15545994 Free PMC article.

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