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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Sadik A, Somarribas Patterson LF, Öztürk S, Mohapatra SR, Panitz V, Secker PF, Pfänder P, Loth S, Salem H, Prentzell MT, Berdel B, Iskar M, Faessler E, Reuter F, Kirst I, Kalter V, Foerster KI, Jäger E, Guevara CR, Sobeh M, Hielscher T, Poschet G, Reinhardt A, Hassel JC, Zapatka M, Hahn U, von Deimling A, Hopf C, Schlichting R, Escher BI, Burhenne J, Haefeli WE, Ishaque N, Böhme A, Schäuble S, Thedieck K, Trump S, Seiffert M, Opitz CA. Sadik A, et al. Among authors: somarribas patterson lf. Cell. 2020 Sep 3;182(5):1252-1270.e34. doi: 10.1016/j.cell.2020.07.038. Epub 2020 Aug 19. Cell. 2020. PMID: 32818467 Free article.
The therapeutic potential of targeting tryptophan catabolism in cancer.
Opitz CA, Somarribas Patterson LF, Mohapatra SR, Dewi DL, Sadik A, Platten M, Trump S. Opitz CA, et al. Among authors: somarribas patterson lf. Br J Cancer. 2020 Jan;122(1):30-44. doi: 10.1038/s41416-019-0664-6. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819194 Free PMC article. Review.
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.
Dewi DL, Mohapatra SR, Blanco Cabañes S, Adam I, Somarribas Patterson LF, Berdel B, Kahloon M, Thürmann L, Loth S, Heilmann K, Weichenhan D, Mücke O, Heiland I, Wimberger P, Kuhlmann JD, Kellner KH, Schott S, Plass C, Platten M, Gerhäuser C, Trump S, Opitz CA. Dewi DL, et al. Among authors: somarribas patterson lf. Oncoimmunology. 2017 Jan 3;6(2):e1274477. doi: 10.1080/2162402X.2016.1274477. eCollection 2017. Oncoimmunology. 2017. PMID: 28344890 Free PMC article.
Metabolic regulation of the cancer-immunity cycle.
Somarribas Patterson LF, Vardhana SA. Somarribas Patterson LF, et al. Trends Immunol. 2021 Nov;42(11):975-993. doi: 10.1016/j.it.2021.09.002. Epub 2021 Oct 2. Trends Immunol. 2021. PMID: 34610889 Free PMC article. Review.