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Identification of an Optimal TLR8 Ligand by Alternating the Position of 2'-O-Ribose Methylation.
Int J Mol Sci. 2022 Sep 22;23(19):11139. doi: 10.3390/ijms231911139.
Int J Mol Sci. 2022.
PMID: 36232437
Free PMC article.
TLR8 is activated by 5'-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway.
Köllisch G, Solis FV, Obermann HL, Eckert J, Müller T, Vierbuchen T, Rickmeyer T, Muche S, Przyborski JM, Heine H, Kaufmann A, Baumeister S, Lingelbach K, Bauer S.
Köllisch G, et al. Among authors: solis fv.
Cell Rep. 2022 Apr 12;39(2):110691. doi: 10.1016/j.celrep.2022.110691.
Cell Rep. 2022.
PMID: 35417716
Free article.
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