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Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: solin o. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.
Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180.
Dickens AM, Vainio S, Marjamäki P, Johansson J, Lehtiniemi P, Rokka J, Rinne J, Solin O, Haaparanta-Solin M, Jones PA, Trigg W, Anthony DC, Airas L. Dickens AM, et al. Among authors: solin o. J Nucl Med. 2014 Mar;55(3):466-72. doi: 10.2967/jnumed.113.125625. Epub 2014 Feb 10. J Nucl Med. 2014. PMID: 24516258 Free article.
Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients.
Golla SS, Boellaard R, Oikonen V, Hoffmann A, van Berckel BN, Windhorst AD, Virta J, Haaparanta-Solin M, Luoto P, Savisto N, Solin O, Valencia R, Thiele A, Eriksson J, Schuit RC, Lammertsma AA, Rinne JO. Golla SS, et al. Among authors: solin o. J Cereb Blood Flow Metab. 2015 May;35(5):766-72. doi: 10.1038/jcbfm.2014.261. Epub 2015 Feb 4. J Cereb Blood Flow Metab. 2015. PMID: 25649991 Free PMC article. Clinical Trial.
Parametric Binding Images of the TSPO Ligand 18F-DPA-714.
Golla SS, Boellaard R, Oikonen V, Hoffmann A, van Berckel BN, Windhorst AD, Virta J, Te Beek ET, Groeneveld GJ, Haaparanta-Solin M, Luoto P, Savisto N, Solin O, Valencia R, Thiele A, Eriksson J, Schuit RC, Lammertsma AA, Rinne JO. Golla SS, et al. Among authors: solin o. J Nucl Med. 2016 Oct;57(10):1543-1547. doi: 10.2967/jnumed.116.173013. Epub 2016 Jun 3. J Nucl Med. 2016. PMID: 27261521 Free article.
Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats.
Keller T, Krzyczmonik A, Forsback S, Picón FRL, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O. Keller T, et al. Among authors: solin o. Mol Imaging Biol. 2017 Oct;19(5):736-745. doi: 10.1007/s11307-016-1040-z. Mol Imaging Biol. 2017. PMID: 28083825 Free PMC article.
[18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease.
Keller T, López-Picón FR, Krzyczmonik A, Forsback S, Kirjavainen AK, Takkinen JS, Alzghool O, Rajander J, Teperi S, Cacheux F, Damont A, Dollé F, Rinne JO, Solin O, Haaparanta-Solin M. Keller T, et al. Among authors: solin o. Nucl Med Biol. 2018 Dec;67:1-9. doi: 10.1016/j.nucmedbio.2018.09.001. Epub 2018 Sep 26. Nucl Med Biol. 2018. PMID: 30317069 Free article.
Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist.
Zhang L, Zhuang X, Kotitalo P, Keller T, Krzyczmonik A, Haaparanta-Solin M, Solin O, Forsback S, Grönroos TJ, Han C, López-Picón FR, Xia H. Zhang L, et al. Among authors: solin o. Theranostics. 2021 Jan 1;11(3):1147-1161. doi: 10.7150/thno.52197. eCollection 2021. Theranostics. 2021. PMID: 33391526 Free PMC article.
Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer's Disease Model Mice and Healthy Controls.
López-Picón FR, Keller T, Bocancea D, Helin JS, Krzyczmonik A, Helin S, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O. López-Picón FR, et al. Among authors: solin o. Mol Imaging Biol. 2022 Feb;24(1):157-166. doi: 10.1007/s11307-021-01646-5. Epub 2021 Sep 20. Mol Imaging Biol. 2022. PMID: 34542805 Free PMC article.
197 results