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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Mannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adults.
Garcia-Laorden MI, Sole-Violan J, Rodriguez de Castro F, Aspa J, Briones ML, Garcia-Saavedra A, Rajas O, Blanquer J, Caballero-Hidalgo A, Marcos-Ramos JA, Hernandez-Lopez J, Rodriguez-Gallego C. Garcia-Laorden MI, et al. J Allergy Clin Immunol. 2008 Aug;122(2):368-74, 374.e1-2. doi: 10.1016/j.jaci.2008.05.037. Epub 2008 Jun 25. J Allergy Clin Immunol. 2008. PMID: 18582923
Genetic variability in the severity and outcome of community-acquired pneumonia.
Solé-Violán J, de Castro Fv, García-Laorden MI, Blanquer J, Aspa J, Borderías L, Briones ML, Rajas O, Carrondo IM, Marcos-Ramos JA, Ferrer Agüero JM, Garcia-Saavedra A, Fiuza MD, Caballero-Hidalgo A, Rodriguez-Gallego C. Solé-Violán J, et al. Respir Med. 2010 Mar;104(3):440-7. doi: 10.1016/j.rmed.2009.10.009. Epub 2009 Nov 8. Respir Med. 2010. PMID: 19900796 Free article.
Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia: a prospective, observational, genetic study.
García-Laorden MI, Rodríguez de Castro F, Solé-Violán J, Rajas O, Blanquer J, Borderías L, Aspa J, Briones ML, Saavedra P, Marcos-Ramos JA, González-Quevedo N, Sologuren I, Herrera-Ramos E, Ferrer JM, Rello J, Rodríguez-Gallego C. García-Laorden MI, et al. Crit Care. 2011;15(1):R57. doi: 10.1186/cc10030. Epub 2011 Feb 10. Crit Care. 2011. PMID: 21310059 Free PMC article.
The Fcγ receptor IIA-H/H131 genotype is associated with bacteremia in pneumococcal community-acquired pneumonia.
Solé-Violán J, García-Laorden MI, Marcos-Ramos JA, de Castro FR, Rajas O, Borderías L, Briones ML, Herrera-Ramos E, Blanquer J, Aspa J, Florido Y, García-Bello MA, Ferrer-Agüero JM, Sologuren I, Rodriguez-Gallego C. Solé-Violán J, et al. Crit Care Med. 2011 Jun;39(6):1388-93. doi: 10.1097/CCM.0b013e31820eda74. Crit Care Med. 2011. PMID: 21317643
Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia.
Martín-Loeches I, Solé-Violán J, Rodríguez de Castro F, García-Laorden MI, Borderías L, Blanquer J, Rajas O, Briones ML, Aspa J, Herrera-Ramos E, Marcos-Ramos JA, Sologuren I, González-Quevedo N, Ferrer-Agüero JM, Noda J, Rodríguez-Gallego C. Martín-Loeches I, et al. Intensive Care Med. 2012 Feb;38(2):256-62. doi: 10.1007/s00134-011-2406-y. Epub 2011 Nov 24. Intensive Care Med. 2012. PMID: 22113815
The role of mannose-binding lectin in pneumococcal infection.
García-Laorden MI, Rodríguez de Castro F, Solé-Violán J, Payeras A, Briones ML, Borderías L, Aspa J, Blanquer J, Rajas O, Marcos-Ramos JA, Herrera-Ramos E, García-Bello MA, Noda J, Ferrer JM, Rello J, Rodríguez-Gallego C. García-Laorden MI, et al. Eur Respir J. 2013 Jan;41(1):131-9. doi: 10.1183/09031936.00174111. Epub 2012 Apr 20. Eur Respir J. 2013. PMID: 22523362 Free article.
250 results