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An image analysis toolbox for high-throughput C. elegans assays.
Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE. Wählby C, et al. Among authors: sokolnicki kl. Nat Methods. 2012 Apr 22;9(7):714-6. doi: 10.1038/nmeth.1984. Nat Methods. 2012. PMID: 22522656 Free PMC article.
Annotated high-throughput microscopy image sets for validation.
Ljosa V, Sokolnicki KL, Carpenter AE. Ljosa V, et al. Among authors: sokolnicki kl. Nat Methods. 2012 Jun 28;9(7):637. doi: 10.1038/nmeth.2083. Nat Methods. 2012. PMID: 22743765 Free PMC article. No abstract available.
High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.
Wählby C, Conery AL, Bray MA, Kamentsky L, Larkins-Ford J, Sokolnicki KL, Veneskey M, Michaels K, Carpenter AE, O'Rourke EJ. Wählby C, et al. Among authors: sokolnicki kl. Methods. 2014 Aug 1;68(3):492-9. doi: 10.1016/j.ymeth.2014.04.017. Epub 2014 Apr 28. Methods. 2014. PMID: 24784529 Free PMC article.
Multiplex cytological profiling assay to measure diverse cellular states.
Gustafsdottir SM, Ljosa V, Sokolnicki KL, Anthony Wilson J, Walpita D, Kemp MM, Petri Seiler K, Carrel HA, Golub TR, Schreiber SL, Clemons PA, Carpenter AE, Shamji AF. Gustafsdottir SM, et al. Among authors: sokolnicki kl. PLoS One. 2013 Dec 2;8(12):e80999. doi: 10.1371/journal.pone.0080999. eCollection 2013. PLoS One. 2013. PMID: 24312513 Free PMC article.
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.
Bray MA, Gustafsdottir SM, Rohban MH, Singh S, Ljosa V, Sokolnicki KL, Bittker JA, Bodycombe NE, Dancík V, Hasaka TP, Hon CS, Kemp MM, Li K, Walpita D, Wawer MJ, Golub TR, Schreiber SL, Clemons PA, Shamji AF, Carpenter AE. Bray MA, et al. Among authors: sokolnicki kl. Gigascience. 2017 Dec 1;6(12):1-5. doi: 10.1093/gigascience/giw014. Gigascience. 2017. PMID: 28327978 Free PMC article.
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.
Wawer MJ, Li K, Gustafsdottir SM, Ljosa V, Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E, Taylor B, Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V, Narayan R, Subramanian A, Winckler W, Golub TR, Carpenter AE, Shamji AF, Schreiber SL, Clemons PA. Wawer MJ, et al. Among authors: sokolnicki kl. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):10911-6. doi: 10.1073/pnas.1410933111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024206 Free PMC article.
A fingerprint pair analysis of hERG inhibition data.
Springer C, Sokolnicki KL. Springer C, et al. Among authors: sokolnicki kl. Chem Cent J. 2013 Oct 21;7(1):167. doi: 10.1186/1752-153X-7-167. Chem Cent J. 2013. PMID: 24144230 Free PMC article.