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Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29684-29690. doi: 10.1073/pnas.2007213117. Epub 2020 Nov 12.
Proc Natl Acad Sci U S A. 2020.
PMID: 33184177
Free PMC article.
A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Opitz R, Müller M, Reuter C, Barone M, Soicke A, Roske Y, Piotukh K, Huy P, Beerbaum M, Wiesner B, Beyermann M, Schmieder P, Freund C, Volkmer R, Oschkinat H, Schmalz HG, Kühne R.
Opitz R, et al. Among authors: soicke a.
Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5011-6. doi: 10.1073/pnas.1422054112. Epub 2015 Apr 6.
Proc Natl Acad Sci U S A. 2015.
PMID: 25848013
Free PMC article.
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Design and Stereoselective Synthesis of ProM-2: A Spirocyclic Diproline Mimetic with Polyproline Type II (PPII) Helix Conformation.
Reuter C, Opitz R, Soicke A, Dohmen S, Barone M, Chiha S, Klein MT, Neudörfl JM, Kühne R, Schmalz HG.
Reuter C, et al. Among authors: soicke a.
Chemistry. 2015 Jun 1;21(23):8464-70. doi: 10.1002/chem.201406493. Epub 2015 Apr 23.
Chemistry. 2015.
PMID: 25906737
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Palladium-catalyzed cyanomethylation of aryl halides through domino Suzuki coupling-isoxazole fragmentation.
Velcicky J, Soicke A, Steiner R, Schmalz HG.
Velcicky J, et al. Among authors: soicke a.
J Am Chem Soc. 2011 May 11;133(18):6948-51. doi: 10.1021/ja201743j. Epub 2011 Apr 19.
J Am Chem Soc. 2011.
PMID: 21504197
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