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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N. Nomura M, et al. Among authors: soga t. Nat Commun. 2023 Dec 13;14(1):8095. doi: 10.1038/s41467-023-43630-3. Nat Commun. 2023. PMID: 38092728 Free PMC article.
mTORC1 is essential for leukemia propagation but not stem cell self-renewal.
Hoshii T, Tadokoro Y, Naka K, Ooshio T, Muraguchi T, Sugiyama N, Soga T, Araki K, Yamamura K, Hirao A. Hoshii T, et al. Among authors: soga t. J Clin Invest. 2012 Jun;122(6):2114-29. doi: 10.1172/JCI62279. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622041 Free PMC article.
Microhomology-assisted scarless genome editing in human iPSCs.
Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K. Kim SI, et al. Among authors: soga t. Nat Commun. 2018 Mar 5;9(1):939. doi: 10.1038/s41467-018-03044-y. Nat Commun. 2018. PMID: 29507284 Free PMC article.
PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N. Morita M, et al. Among authors: soga t. Cancer Cell. 2018 Mar 12;33(3):355-367.e7. doi: 10.1016/j.ccell.2018.02.004. Cancer Cell. 2018. PMID: 29533781 Free article.
Autophagy regulates lipid metabolism through selective turnover of NCoR1.
Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M. Saito T, et al. Among authors: soga t. Nat Commun. 2019 Apr 5;10(1):1567. doi: 10.1038/s41467-019-08829-3. Nat Commun. 2019. PMID: 30952864 Free PMC article.
669 results