Soga S - Search Results

1

Antibody informatics for drug discovery.

Shirai H, Prades C, Vita R, Marcatili P, Popovic B, Xu J, Overington JP, Hirayama K, Soga S, Tsunoyama K, Clark D, Lefranc MP, Ikeda K. Shirai H, et al. Among authors: soga s. Biochim Biophys Acta. 2014 Nov;1844(11):2002-2015. doi: 10.1016/j.bbapap.2014.07.006. Epub 2014 Aug 8. Biochim Biophys Acta. 2014. PMID: 25110827 Review.

2

Use of amino acid composition to predict ligand-binding sites.

Soga S, Shirai H, Kobori M, Hirayama N. Soga S, et al. J Chem Inf Model. 2007 Mar-Apr;47(2):400-6. doi: 10.1021/ci6002202. Epub 2007 Jan 23. J Chem Inf Model. 2007. PMID: 17243757

3

Identification of the druggable concavity in homology models using the PLB index.

Soga S, Shirai H, Kobori M, Hirayama N. Soga S, et al. J Chem Inf Model. 2007 Nov-Dec;47(6):2287-92. doi: 10.1021/ci7002363. Epub 2007 Oct 13. J Chem Inf Model. 2007. PMID: 17935312

4

Chemocavity: specific concavity in protein reserved for the binding of biologically functional small molecules.

Soga S, Shirai H, Kobori M, Hirayama N. Soga S, et al. J Chem Inf Model. 2008 Aug;48(8):1679-85. doi: 10.1021/ci800113c. Epub 2008 Jul 22. J Chem Inf Model. 2008. PMID: 18642867

5

Use of amino acid composition to predict epitope residues of individual antibodies.

Soga S, Kuroda D, Shirai H, Kobori M, Hirayama N. Soga S, et al. Protein Eng Des Sel. 2010 Jun;23(6):441-8. doi: 10.1093/protein/gzq014. Epub 2010 Mar 19. Protein Eng Des Sel. 2010. PMID: 20304974

6

Computational design, construction, and characterization of a set of specificity determining residues in protein-protein interactions.

Nagao C, Izako N, Soga S, Khan SH, Kawabata S, Shirai H, Mizuguchi K. Nagao C, et al. Among authors: soga s. Proteins. 2012 Oct;80(10):2426-36. doi: 10.1002/prot.24127. Epub 2012 Jul 10. Proteins. 2012. PMID: 22674858

7

Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex.

Kiyoshi M, Caaveiro JM, Miura E, Nagatoishi S, Nakakido M, Soga S, Shirai H, Kawabata S, Tsumoto K. Kiyoshi M, et al. Among authors: soga s. PLoS One. 2014 Jan 27;9(1):e87099. doi: 10.1371/journal.pone.0087099. eCollection 2014. PLoS One. 2014. PMID: 24475232 Free PMC article.

8

Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations.

Yoshida K, Kuroda D, Kiyoshi M, Nakakido M, Nagatoishi S, Soga S, Shirai H, Tsumoto K. Yoshida K, et al. Among authors: soga s. Sci Rep. 2019 Mar 14;9(1):4482. doi: 10.1038/s41598-019-40461-5. Sci Rep. 2019. PMID: 30872635 Free PMC article.

9

Generation and Characterization of a Novel Anti-Rat TLR4/MD2 Antibody with Potent Neutralizing Activity In Vivo.

Sato M, Takeuchi S, Soga S, Aoyama K, Suzuki J. Sato M, et al. Among authors: soga s. Monoclon Antib Immunodiagn Immunother. 2020 Dec;39(6):217-221. doi: 10.1089/mab.2020.0020. Epub 2020 Dec 7. Monoclon Antib Immunodiagn Immunother. 2020. PMID: 33290148

10

Novel TLR2xTLR4 Bispecific Antibody Inhibits Bacterial Sepsis.

Sato M, Takeuchi S, Moriya R, Kito T, Soga S, Aoyama K, Suzuki J. Sato M, et al. Among authors: soga s. Monoclon Antib Immunodiagn Immunother. 2021 Feb;40(1):6-10. doi: 10.1089/mab.2020.0025. Epub 2020 Dec 21. Monoclon Antib Immunodiagn Immunother. 2021. PMID: 33347385

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