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Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance.
Socodato R, Almeida TO, Portugal CC, Santos ECS, Tedim-Moreira J, Galvão-Ferreira J, Canedo T, Baptista FI, Magalhães A, Ambrósio AF, Brakebusch C, Rubinstein B, Moreira IS, Summavielle T, Pinto IM, Relvas JB. Socodato R, et al. Cell Rep. 2023 Dec 26;42(12):113447. doi: 10.1016/j.celrep.2023.113447. Epub 2023 Nov 18. Cell Rep. 2023. PMID: 37980559 Free article.
Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion.
Socodato R, Santiago FN, Portugal CC, Domingues AF, Santiago AR, Relvas JB, Ambrósio AF, Paes-de-Carvalho R. Socodato R, et al. J Biol Chem. 2012 Nov 9;287(46):38680-94. doi: 10.1074/jbc.M112.353961. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992730 Free PMC article.
Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells.
Coelho-Santos V, Socodato R, Portugal C, Leitão RA, Rito M, Barbosa M, Couraud PO, Romero IA, Weksler B, Minshall RD, Fontes-Ribeiro C, Summavielle T, Relvas JB, Silva AP. Coelho-Santos V, et al. Among authors: socodato r. Cell Mol Life Sci. 2016 Dec;73(24):4701-4716. doi: 10.1007/s00018-016-2301-3. Epub 2016 Jul 4. Cell Mol Life Sci. 2016. PMID: 27376435
43 results