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Tetracycline repurposing in neurodegeneration: focus on Parkinson's disease.
Bortolanza M, Nascimento GC, Socias SB, Ploper D, Chehín RN, Raisman-Vozari R, Del-Bel E. Bortolanza M, et al. Among authors: socias sb. J Neural Transm (Vienna). 2018 Oct;125(10):1403-1415. doi: 10.1007/s00702-018-1913-1. Epub 2018 Aug 14. J Neural Transm (Vienna). 2018. PMID: 30109452 Review.
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
González-Lizárraga F, Socías SB, Ávila CL, Torres-Bugeau CM, Barbosa LR, Binolfi A, Sepúlveda-Díaz JE, Del-Bel E, Fernandez CO, Papy-Garcia D, Itri R, Raisman-Vozari R, Chehín RN. González-Lizárraga F, et al. Among authors: socias sb. Sci Rep. 2017 Feb 3;7:41755. doi: 10.1038/srep41755. Sci Rep. 2017. PMID: 28155912 Free PMC article.
Structural characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase protofibrils preventing α-synuclein oligomeric species toxicity.
Ávila CL, Torres-Bugeau CM, Barbosa LR, Sales EM, Ouidja MO, Socías SB, Celej MS, Raisman-Vozari R, Papy-Garcia D, Itri R, Chehín RN. Ávila CL, et al. Among authors: socias sb. J Biol Chem. 2014 May 16;289(20):13838-50. doi: 10.1074/jbc.M113.544288. Epub 2014 Mar 26. J Biol Chem. 2014. PMID: 24671416 Free PMC article.
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity.
Medina L, González-Lizárraga F, Dominguez-Meijide A, Ploper D, Parrales V, Sequeira S, Cima-Omori MS, Zweckstetter M, Del Bel E, Michel PP, Outeiro TF, Raisman-Vozari R, Chehín R, Socias SB. Medina L, et al. Among authors: socias sb. Front Aging Neurosci. 2021 Mar 22;13:635760. doi: 10.3389/fnagi.2021.635760. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33828477 Free PMC article.
Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound.
Tomas-Grau R, González-Lizárraga F, Ploper D, Avila CL, Socías SB, Besnault P, Tourville A, Mella RM, Villacé P, Salado C, Rose C, Seon-Méniel B, Brunel JM, Ferrié L, Raisman-Vozari R, Michel PP, Figadère B, Chehín R. Tomas-Grau R, et al. Among authors: socias sb. Cells. 2022 Sep 4;11(17):2759. doi: 10.3390/cells11172759. Cells. 2022. PMID: 36078167 Free PMC article.
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