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Year Number of Results
2015 1
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2020 10
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49 results

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Page 1
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action.
Kazakova A, Frydrych I, Jakubcová N, Pokorný J, Lišková B, Gurská S, Džubák P, Hajdúch M, Urban M. Kazakova A, et al. Among authors: gurska s. Eur J Med Chem. 2024 Apr 5;269:116336. doi: 10.1016/j.ejmech.2024.116336. Epub 2024 Mar 18. Eur J Med Chem. 2024. PMID: 38520761 Free article.
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation.
Velavalapalli VM, Maddipati VC, Gurská S, Annadurai N, Lišková B, Katari NK, Džubák P, Hajdúch M, Das V, Gundla R. Velavalapalli VM, et al. Among authors: gurska s. ACS Omega. 2024 Feb 7;9(7):8067-8081. doi: 10.1021/acsomega.3c08343. eCollection 2024 Feb 20. ACS Omega. 2024. PMID: 38405484 Free PMC article.
Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives.
Gutiérrez JE, Ramírez H, Fernandez-Moreira E, Acosta ME, Mijares MR, De Sanctis JB, Gurská S, Džubák P, Hajdúch M, Labrador-Fagúndez L, Stella BG, Díaz-Pérez LJ, Benaim G, Charris JE. Gutiérrez JE, et al. Among authors: gurska s. Pharmaceuticals (Basel). 2023 Dec 9;16(12):1709. doi: 10.3390/ph16121709. Pharmaceuticals (Basel). 2023. PMID: 38139835 Free PMC article.
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone).
Ivasechko I, Lozynskyi A, Senkiv J, Roszczenko P, Kozak Y, Finiuk N, Klyuchivska O, Kashchak N, Manko N, Maslyak Z, Lesyk D, Karkhut A, Polovkovych S, Czarnomysy R, Szewczyk O, Kozytskiy A, Karpenko O, Khyluk D, Gzella A, Bielawski K, Bielawska A, Dzubak P, Gurska S, Hajduch M, Stoika R, Lesyk R. Ivasechko I, et al. Among authors: gurska s. Eur J Med Chem. 2023 Apr 5;252:115304. doi: 10.1016/j.ejmech.2023.115304. Epub 2023 Mar 24. Eur J Med Chem. 2023. PMID: 37001390 Free article.
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition.
Jurášek M, Řehulka J, Hrubá L, Ivanová A, Gurská S, Mokshyna O, Trousil P, Huml L, Polishchuk P, Hajdúch M, Drašar PB, Džubák P. Jurášek M, et al. Among authors: gurska s. Bioorg Chem. 2023 Feb;131:106334. doi: 10.1016/j.bioorg.2022.106334. Epub 2022 Dec 23. Bioorg Chem. 2023. PMID: 36592487 Free article.
Cannabinoid receptor 2 expression in early-stage non-small cell lung cancers identifies patients with good prognosis and longer survival.
Vidlarova M, Berta E, Prasil P, Prokopova A, Gurska S, Khoylou M, Rehulkova A, Kourilova P, Chudacek J, Szkorupa M, Klein J, Skarda J, Srovnal J, Hajduch M. Vidlarova M, et al. Among authors: gurska s. Transl Lung Cancer Res. 2022 Oct;11(10):2040-2050. doi: 10.21037/tlcr-22-247. Transl Lung Cancer Res. 2022. PMID: 36386452 Free PMC article.
Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage.
Gutiérrez JE, Fernandez-Moreira E, Rodríguez MA, Mijares MR, De Sanctis JB, Gurská S, Džubák P, Hajdůch M, Bruno-Colmenarez J, Rojas L, Deffieux D, Pouységu L, Quideau S, Charris J, Ramírez H. Gutiérrez JE, et al. Among authors: gurska s. Pharmaceuticals (Basel). 2022 Oct 8;15(10):1234. doi: 10.3390/ph15101234. Pharmaceuticals (Basel). 2022. PMID: 36297346 Free PMC article.
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes.
Borková L, Frydrych I, Vránová B, Jakubcová N, Lišková B, Gurská S, Džubák P, Pavliš P, Hajdúch M, Urban M. Borková L, et al. Among authors: gurska s. Eur J Med Chem. 2022 Dec 15;244:114850. doi: 10.1016/j.ejmech.2022.114850. Epub 2022 Oct 20. Eur J Med Chem. 2022. PMID: 36283179
49 results