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Neuroprotection by pharmacologic blockade of the GAPDH death cascade.
Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Hara MR, et al. Among authors: snyder sh. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3887-9. doi: 10.1073/pnas.0511321103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505364 Free PMC article.
Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH.
Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Bae BI, et al. Among authors: snyder sh. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3405-9. doi: 10.1073/pnas.0511316103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492755 Free PMC article.
Nitric oxide-GAPDH-Siah: a novel cell death cascade.
Hara MR, Snyder SH. Hara MR, et al. Among authors: snyder sh. Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):527-38. doi: 10.1007/s10571-006-9011-6. Epub 2006 Apr 22. Cell Mol Neurobiol. 2006. PMID: 16633896 Review.
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.
Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Sen N, et al. Among authors: snyder sh. Nat Cell Biol. 2008 Jul;10(7):866-73. doi: 10.1038/ncb1747. Epub 2008 Jun 15. Nat Cell Biol. 2008. PMID: 18552833 Free PMC article.
S-nitrosylation/activation of COX-2 mediates NMDA neurotoxicity.
Tian J, Kim SF, Hester L, Snyder SH. Tian J, et al. Among authors: snyder sh. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10537-40. doi: 10.1073/pnas.0804852105. Epub 2008 Jul 23. Proc Natl Acad Sci U S A. 2008. PMID: 18650379 Free PMC article.
GAPDH mediates nitrosylation of nuclear proteins.
Kornberg MD, Sen N, Hara MR, Juluri KR, Nguyen JV, Snowman AM, Law L, Hester LD, Snyder SH. Kornberg MD, et al. Among authors: snyder sh. Nat Cell Biol. 2010 Nov;12(11):1094-100. doi: 10.1038/ncb2114. Epub 2010 Oct 24. Nat Cell Biol. 2010. PMID: 20972425 Free PMC article.
1,153 results