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De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Yang B, Chatoff A, Crispim CV, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Lyssiotis CA, Chandran UR, Snyder NW, Aird KM. Tangudu NK, et al. Among authors: snyder nw. Cancer Res Commun. 2024 May 2;4(5):1174-1188. doi: 10.1158/2767-9764.CRC-23-0450. Cancer Res Commun. 2024. PMID: 38626341 Free PMC article.
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation.
Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK, Cole AR, Megill E, Kantner D, Chatoff A, Ahmad H, Marcinkiewicz MM, Disharoon JA, Graff S, Dahl ES, Hempel N, Stallaert W, Sidoli S, Bitler BG, Long DT, Snyder NW, Aird KM. Uboveja A, et al. Among authors: snyder nw. bioRxiv [Preprint]. 2024 Feb 11:2024.02.06.578742. doi: 10.1101/2024.02.06.578742. bioRxiv. 2024. PMID: 38370789 Free PMC article. Preprint.
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Among authors: snyder nw. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
299 results