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Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY. Tobe BTD, et al. Among authors: snyder ey. Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12. Proc Natl Acad Sci U S A. 2017. PMID: 28500272 Free PMC article.
Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia.
Nomoto M, Konopaske GT, Yamashita N, Aoki R, Jitsuki-Takahashi A, Nakamura H, Makihara H, Saito M, Saigusa Y, Nakamura F, Watanabe K, Baba T, Benes FM, Tobe BTD, Pernia CD, Coyle JT, Sidman RL, Hirayasu Y, Snyder EY, Goshima Y. Nomoto M, et al. Among authors: snyder ey. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2100032118. doi: 10.1073/pnas.2100032118. Proc Natl Acad Sci U S A. 2021. PMID: 34330827 Free PMC article.
Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion.
Zhao WN, Tobe BTD, Udeshi ND, Xuan LL, Pernia CD, Zolg DP, Roberts AJ, Mani D, Blumenthal SR, Kurtser I, Patnaik D, Gaisina I, Bishop J, Sheridan SD, Lalonde J, Carr SA, Snyder EY, Haggarty SJ. Zhao WN, et al. Among authors: snyder ey. Transl Psychiatry. 2020 Feb 24;10(1):76. doi: 10.1038/s41398-020-0753-6. Transl Psychiatry. 2020. PMID: 32094324 Free PMC article.
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway.
Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ. Imitola J, et al. Among authors: snyder ey. Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18117-22. doi: 10.1073/pnas.0408258102. Epub 2004 Dec 17. Proc Natl Acad Sci U S A. 2004. PMID: 15608062 Free PMC article.
Stem cells and spinal cord repair.
Snyder EY, Teng YD. Snyder EY, et al. N Engl J Med. 2012 May 17;366(20):1940-2. doi: 10.1056/NEJMcibr1200138. N Engl J Med. 2012. PMID: 22591301 No abstract available.
228 results