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Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids.
Michalak EM, Milevskiy MJG, Joyce RM, Dekkers JF, Jamieson PR, Pal B, Dawson CA, Hu Y, Orkin SH, Alexander WS, Lindeman GJ, Smyth GK, Visvader JE. Michalak EM, et al. Among authors: smyth gk. PLoS Biol. 2018 Aug 6;16(8):e2004986. doi: 10.1371/journal.pbio.2004986. eCollection 2018 Aug. PLoS Biol. 2018. PMID: 30080881 Free PMC article.
Generation of a functional mammary gland from a single stem cell.
Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, Wu L, Lindeman GJ, Visvader JE. Shackleton M, et al. Among authors: smyth gk. Nature. 2006 Jan 5;439(7072):84-8. doi: 10.1038/nature04372. Nature. 2006. PMID: 16397499
Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity.
Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M, Hilton AA, Hyland CD, Smyth GK, Corbin JE, Metcalf D, Alexander WS, Hilton DJ. Majewski IJ, et al. Among authors: smyth gk. PLoS Biol. 2008 Apr 15;6(4):e93. doi: 10.1371/journal.pbio.0060093. PLoS Biol. 2008. PMID: 18416604 Free PMC article.
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.
Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ; kConFab; Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ. Lim E, et al. Among authors: smyth gk. Nat Med. 2009 Aug;15(8):907-13. doi: 10.1038/nm.2000. Epub 2009 Aug 2. Nat Med. 2009. PMID: 19648928
Control of mammary stem cell function by steroid hormone signalling.
Asselin-Labat ML, Vaillant F, Sheridan JM, Pal B, Wu D, Simpson ER, Yasuda H, Smyth GK, Martin TJ, Lindeman GJ, Visvader JE. Asselin-Labat ML, et al. Among authors: smyth gk. Nature. 2010 Jun 10;465(7299):798-802. doi: 10.1038/nature09027. Epub 2010 Apr 11. Nature. 2010. PMID: 20383121
262 results