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Insights into the ancestry evolution of the Mycobacterium tuberculosis complex from analysis of Mycobacterium riyadhense.
Guan Q, Garbati M, Mfarrej S, AlMutairi T, Laval T, Singh A, Fagbo S, Smyth A, Browne JA, urRahman MA, Alruwaili A, Hoosen A, Meehan CJ, Nakajima C, Suzuki Y, Demangel C, Bhatt A, Gordon SV, AlAsmari F, Pain A. Guan Q, et al. Among authors: smyth a. NAR Genom Bioinform. 2021 Aug 11;3(3):lqab070. doi: 10.1093/nargab/lqab070. eCollection 2021 Sep. NAR Genom Bioinform. 2021. PMID: 34396095 Free PMC article.
Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli.
Malone KM, Rue-Albrecht K, Magee DA, Conlon K, Schubert OT, Nalpas NC, Browne JA, Smyth A, Gormley E, Aebersold R, MacHugh DE, Gordon SV. Malone KM, et al. Among authors: smyth a. Microb Genom. 2018 Mar;4(3):e000163. doi: 10.1099/mgen.0.000163. Epub 2018 Mar 20. Microb Genom. 2018. PMID: 29557774 Free PMC article.
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21.
Hackett EE, Charles-Messance H, O'Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ. Hackett EE, et al. Among authors: smyth a. Cell Rep. 2020 Jan 7;30(1):124-136.e4. doi: 10.1016/j.celrep.2019.12.015. Cell Rep. 2020. PMID: 31914380 Free PMC article.
Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle.
Villarreal-Ramos B, Berg S, Whelan A, Holbert S, Carreras F, Salguero FJ, Khatri BL, Malone K, Rue-Albrecht K, Shaughnessy R, Smyth A, Ameni G, Aseffa A, Sarradin P, Winter N, Vordermeier M, Gordon SV. Villarreal-Ramos B, et al. Among authors: smyth a. Sci Rep. 2018 Jan 17;8(1):894. doi: 10.1038/s41598-017-18575-5. Sci Rep. 2018. PMID: 29343690 Free PMC article.
Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.
Queval CJ, Fearns A, Botella L, Smyth A, Schnettger L, Mitermite M, Wooff E, Villarreal-Ramos B, Garcia-Jimenez W, Heunis T, Trost M, Werling D, Salguero FJ, Gordon SV, Gutierrez MG. Queval CJ, et al. Among authors: smyth a. PLoS Pathog. 2021 Mar 15;17(3):e1009410. doi: 10.1371/journal.ppat.1009410. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720986 Free PMC article.
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Ní Cheallaigh C, Sheedy FJ, Harris J, Muñoz-Wolf N, Lee J, West K, McDermott EP, Smyth A, Gleeson LE, Coleman M, Martinez N, Hearnden CH, Tynan GA, Carroll EC, Jones SA, Corr SC, Bernard NJ, Hughes MM, Corcoran SE, O'Sullivan M, Fallon CM, Kornfeld H, Golenbock D, Gordon SV, O'Neill LA, Lavelle EC, Keane J. Ní Cheallaigh C, et al. Among authors: smyth a. Immunity. 2016 Feb 16;44(2):368-79. doi: 10.1016/j.immuni.2016.01.019. Immunity. 2016. PMID: 26885859 Free PMC article.
564 results