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Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma.
Floros KV, Fairchild CK, Li J, Zhang K, Roberts JL, Kurupi R, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Xing Y, Hill RD, Slaughter JM, Shende M, Lorenz MR, Hinojosa MR, Belvin BR, Lai Z, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Valerie K, Li R, Banito A, Poklepovic A, Koblinski JE, Siggers T, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Floros KV, et al. Among authors: smith fry k. bioRxiv [Preprint]. 2024 Apr 27:2024.04.25.591023. doi: 10.1101/2024.04.25.591023. bioRxiv. 2024. PMID: 38712286 Free PMC article. Preprint.
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: smith fry k. Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5. Nat Commun. 2024. PMID: 38326311 Free PMC article.
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: smith fry k. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560242. doi: 10.1101/2023.09.29.560242. bioRxiv. 2023. PMID: 37873234 Free PMC article. Updated. Preprint.
The Influential Role of BCL2 Family Members in Synovial Sarcomagenesis.
Barrott JJ, Zhu JF, Smith-Fry K, Susko AM, Nollner D, Burrell LD, Pozner A, Capecchi MR, Yap JT, Cannon-Albright LA, Deng X, Jones KB. Barrott JJ, et al. Among authors: smith fry k. Mol Cancer Res. 2017 Dec;15(12):1733-1740. doi: 10.1158/1541-7786.MCR-17-0315. Epub 2017 Aug 29. Mol Cancer Res. 2017. PMID: 28851813 Free PMC article.
The Impact of Microenvironment on the Synovial Sarcoma Transcriptome.
Jin H, Barrott JJ, Cable MG, Monument MJ, Lerman DM, Smith-Fry K, Nollner D, Jones KB. Jin H, et al. Among authors: smith fry k. Cancer Microenviron. 2017 Dec;10(1-3):1-7. doi: 10.1007/s12307-017-0192-y. Epub 2017 Apr 13. Cancer Microenviron. 2017. PMID: 28409421 Free PMC article.