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Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation.
Latour YL, Sierra JC, Finley JL, Asim M, Barry DP, Allaman MM, Smith TM, McNamara KM, Luis PB, Schneider C, Jacobse J, Goettel JA, Calcutt MW, Rose KL, Schey KL, Milne GL, Delgado AG, Piazuelo MB, Paul BD, Snyder SH, Gobert AP, Wilson KT. Latour YL, et al. Among authors: smith tm. JCI Insight. 2022 Jun 22;7(12):e155338. doi: 10.1172/jci.insight.155338. JCI Insight. 2022. PMID: 35579952 Free PMC article.
Hypusination Orchestrates the Antimicrobial Response of Macrophages.
Gobert AP, Finley JL, Latour YL, Asim M, Smith TM, Verriere TG, Barry DP, Allaman MM, Delagado AG, Rose KL, Calcutt MW, Schey KL, Sierra JC, Piazuelo MB, Mirmira RG, Wilson KT. Gobert AP, et al. Among authors: smith tm. Cell Rep. 2020 Dec 15;33(11):108510. doi: 10.1016/j.celrep.2020.108510. Cell Rep. 2020. PMID: 33326776 Free PMC article.
Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Gobert AP, Latour YL, Asim M, Barry DP, Allaman MM, Finley JL, Smith TM, McNamara KM, Singh K, Sierra JC, Delgado AG, Luis PB, Schneider C, Washington MK, Piazuelo MB, Zhao S, Coburn LA, Wilson KT. Gobert AP, et al. Among authors: smith tm. Gastroenterology. 2022 Mar;162(3):813-827.e8. doi: 10.1053/j.gastro.2021.11.005. Epub 2021 Nov 10. Gastroenterology. 2022. PMID: 34767785 Free PMC article.
The nutraceutical electrophile scavenger 2-hydroxybenzylamine (2-HOBA) attenuates gastric cancer development caused by Helicobacter pylori.
Gobert AP, Asim M, Smith TM, Williams KJ, Barry DP, Allaman MM, McNamara KM, Hawkins CV, Delgado AG, Blanca Piazuelo M, Rathmacher JA, Wilson KT. Gobert AP, et al. Among authors: smith tm. Biomed Pharmacother. 2023 Feb;158:114092. doi: 10.1016/j.biopha.2022.114092. Epub 2022 Dec 6. Biomed Pharmacother. 2023. PMID: 36493697 Free PMC article.
Epithelial talin-1 protects mice from citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing t cell immunity.
Latour YL, Allaman MM, Barry DP, Smith TM, Williams KJ, McNamara KM, Jacobse J, Goettel JA, Delgado AG, Piazuelo MB, Zhao S, Gobert AP, Wilson KT. Latour YL, et al. Among authors: smith tm. Gut Microbes. 2023 Jan-Dec;15(1):2192623. doi: 10.1080/19490976.2023.2192623. Gut Microbes. 2023. PMID: 36951501 Free PMC article.
Electrophilic reactive aldehydes as a therapeutic target in colorectal cancer prevention and treatment.
Gobert AP, Asim M, Smith TM, Williams KJ, Barry DP, Allaman MM, McNamara KM, Hawkins CV, Delgado AG, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Rathmacher JA, Wilson KT. Gobert AP, et al. Among authors: smith tm. Oncogene. 2023 May;42(20):1685-1691. doi: 10.1038/s41388-023-02691-w. Epub 2023 Apr 10. Oncogene. 2023. PMID: 37037901 Free PMC article.
Hypusination Maintains Intestinal Homeostasis and Prevents Colitis and Carcinogenesis by Enhancing Aldehyde Detoxification.
Gobert AP, Smith TM, Latour YL, Asim M, Barry DP, Allaman MM, Williams KJ, McNamara KM, Delgado AG, Short SP, Mirmira RG, Rose KL, Schey KL, Zagol-Ikapitte I, Coleman JS, Boutaud O, Zhao S, Piazuelo MB, Washington MK, Coburn LA, Wilson KT. Gobert AP, et al. Among authors: smith tm. Gastroenterology. 2023 Sep;165(3):656-669.e8. doi: 10.1053/j.gastro.2023.05.041. Epub 2023 Jun 2. Gastroenterology. 2023. PMID: 37271289
394 results