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Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial.
Han JK, Bachert C, Fokkens W, Desrosiers M, Wagenmann M, Lee SE, Smith SG, Martin N, Mayer B, Yancey SW, Sousa AR, Chan R, Hopkins C; SYNAPSE study investigators. Han JK, et al. Among authors: smith sg. Lancet Respir Med. 2021 Oct;9(10):1141-1153. doi: 10.1016/S2213-2600(21)00097-7. Epub 2021 Apr 16. Lancet Respir Med. 2021. PMID: 33872587
Severe eosinophilic asthma with nasal polyposis: A phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy.
Howarth P, Chupp G, Nelsen LM, Bradford ES, Bratton DJ, Smith SG, Albers FC, Brusselle G, Bachert C. Howarth P, et al. Among authors: smith sg. J Allergy Clin Immunol. 2020 Jun;145(6):1713-1715. doi: 10.1016/j.jaci.2020.02.002. Epub 2020 Feb 19. J Allergy Clin Immunol. 2020. PMID: 32084443 Clinical Trial. No abstract available.
The inflammatory profile of exacerbations in patients with severe refractory eosinophilic asthma receiving mepolizumab (the MEX study): a prospective observational study.
McDowell PJ, Diver S, Yang F, Borg C, Busby J, Brown V, Shrimanker R, Cox C, Brightling CE, Chaudhuri R, Pavord ID, Heaney LG; Medical Research Council: Refractory Asthma Stratification Programme (RASP-UK Consortium). McDowell PJ, et al. Lancet Respir Med. 2021 Oct;9(10):1174-1184. doi: 10.1016/S2213-2600(21)00004-7. Epub 2021 May 7. Lancet Respir Med. 2021. PMID: 33971168
Clinical effects of mepolizumab in patients with severe eosinophilic asthma according to background therapy: A meta-analysis.
Lugogo N, Liu MC, Pavord I, Mitchell PD, Smith SG, Mallett S, Albers FC, Bradford ES, Yancey SW, Bel EH. Lugogo N, et al. Among authors: smith sg. J Allergy Clin Immunol Pract. 2021 Sep;9(9):3506-3509.e3. doi: 10.1016/j.jaip.2021.05.024. Epub 2021 Jun 7. J Allergy Clin Immunol Pract. 2021. PMID: 34111572 Free article. No abstract available.
549 results