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Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.
Walji AM, Sanchez RI, Clas SD, Nofsinger R, de Lera Ruiz M, Li J, Bennet A, John C, Bennett DJ, Sanders JM, Di Marco CN, Kim SH, Balsells J, Ceglia SS, Dang Q, Manser K, Nissley B, Wai JS, Hafey M, Wang J, Chessen G, Templeton A, Higgins J, Smith R, Wu Y, Grobler J, Coleman PJ. Walji AM, et al. ChemMedChem. 2015 Feb;10(2):245-52. doi: 10.1002/cmdc.201402393. Epub 2014 Dec 2. ChemMedChem. 2015. PMID: 25469982
Coated microneedles for transdermal delivery of a potent pharmaceutical peptide.
Kapoor Y, Milewski M, Dick L, Zhang J, Bothe JR, Gehrt M, Manser K, Nissley B, Petrescu I, Johnson P, Burton S, Moseman J, Hua V, Grunewald T, Tomai M, Smith R. Kapoor Y, et al. Biomed Microdevices. 2019 Dec 16;22(1):7. doi: 10.1007/s10544-019-0462-1. Biomed Microdevices. 2019. PMID: 31845070
Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC-HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel.
Savaryn JP, Smith RL, Rosebraugh M, Neenan M, Burton R, Marsh K, Wagner D. Savaryn JP, et al. Among authors: smith rl. Pharmacol Res Perspect. 2024 Apr;12(2):e1190. doi: 10.1002/prp2.1190. Pharmacol Res Perspect. 2024. PMID: 38597598 Free PMC article. Clinical Trial.
1,620 results