Smith RH - Search Results

1

IFN-γ directly inhibits the activity of erythropoietin in human erythroid progenitors.

Araki D, Alvarado LJ, Huntsman HD, Smith RH, Larochelle A. Araki D, et al. Among authors: smith rh. Blood Cells Mol Dis. 2020 Nov;85:102488. doi: 10.1016/j.bcmd.2020.102488. Epub 2020 Aug 21. Blood Cells Mol Dis. 2020. PMID: 32889151 Free PMC article. No abstract available.

2

Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones.

Smith RH, Chen YC, Seifuddin F, Hupalo D, Alba C, Reger R, Tian X, Araki D, Dalgard CL, Childs RW, Pirooznia M, Larochelle A. Smith RH, et al. Genes (Basel). 2020 Dec 13;11(12):1501. doi: 10.3390/genes11121501. Genes (Basel). 2020. PMID: 33322084 Free PMC article. Clinical Trial.

3

Eltrombopag Improves Erythroid Differentiation in a Human Induced Pluripotent Stem Cell Model of Diamond Blackfan Anemia.

Qanash H, Li Y, Smith RH, Linask K, Young-Baird S, Hakami W, Keyvanfar K, Choy JS, Zou J, Larochelle A. Qanash H, et al. Among authors: smith rh. Cells. 2021 Mar 26;10(4):734. doi: 10.3390/cells10040734. Cells. 2021. PMID: 33810313 Free PMC article.

4

NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia.

Araki D, Fu JF, Huntsman H, Cordes S, Seifuddin F, Alvarado LJ, Cheruku PS, Cash A, Traba J, Li Y, Pirooznia M, Smith RH, Larochelle A. Araki D, et al. Among authors: smith rh. Stem Cell Reports. 2021 Sep 14;16(9):2336-2350. doi: 10.1016/j.stemcr.2021.08.001. Epub 2021 Aug 26. Stem Cell Reports. 2021. PMID: 34450041 Free PMC article.

5

Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells.

Guenther KL, Cheruku PS, Cash A, Smith RH, Alvarado LJ, Burkett S, Townsley DM, Winkler T, Larochelle A. Guenther KL, et al. Among authors: smith rh. Exp Hematol. 2019 May;73:1-6.e6. doi: 10.1016/j.exphem.2019.03.002. Epub 2019 Apr 13. Exp Hematol. 2019. PMID: 30986494 Free PMC article.

6

Genome editing in human hematopoietic stem and progenitor cells via CRISPR-Cas9-mediated homology-independent targeted integration.

Bloomer H, Smith RH, Hakami W, Larochelle A. Bloomer H, et al. Among authors: smith rh. Mol Ther. 2021 Apr 7;29(4):1611-1624. doi: 10.1016/j.ymthe.2020.12.010. Epub 2020 Dec 10. Mol Ther. 2021. PMID: 33309880 Free PMC article.

7

Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1.

Smith RH, Bloomer H, Fink D, Keyvanfar K, Nasimuzzaman M, Sancheznieto F, Dutta R, Guenther Bui K, Alvarado LJ, Bauer TR Jr, Hickstein DD, Russell DW, Malik P, van der Loo JCM, Highfill SL, Kuhns DB, Pirooznia M, Larochelle A. Smith RH, et al. Hum Gene Ther. 2022 Dec;33(23-24):1293-1304. doi: 10.1089/hum.2022.065. Epub 2022 Nov 1. Hum Gene Ther. 2022. PMID: 36094106 Free PMC article.

8

Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia.

Çelik H, Lindblad KE, Popescu B, Gui G, Goswami M, Valdez J, DeStefano C, Lai C, Thompson J, Ghannam JY, Fantoni G, Biancotto A, Candia J, Cheung F, Sukumar G, Dalgard CL, Smith RH, Larochelle A, Dillon LW, Hourigan CS. Çelik H, et al. Among authors: smith rh. Blood Adv. 2020 Jan 28;4(2):367-379. doi: 10.1182/bloodadvances.2019001124. Blood Adv. 2020. PMID: 31985806 Free PMC article.

9

Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency.

Nasimuzzaman M, Lynn D, Ernst R, Beuerlein M, Smith RH, Shrestha A, Cross S, Link K, Lutzko C, Nordling D, Russell DW, Larochelle A, Malik P, Van der Loo JC. Nasimuzzaman M, et al. Among authors: smith rh. Mol Ther Methods Clin Dev. 2016 Mar 16;3:16004. doi: 10.1038/mtm.2016.4. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27722179 Free PMC article.

10

Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2.

Chiorini JA, Zimmermann B, Yang L, Smith RH, Ahearn A, Herberg F, Kotin RM. Chiorini JA, et al. Among authors: smith rh. Mol Cell Biol. 1998 Oct;18(10):5921-9. doi: 10.1128/MCB.18.10.5921. Mol Cell Biol. 1998. PMID: 9742109 Free PMC article.

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