Smith LA - Search Results

1

Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism.

Webb RP, Smith TJ, Smith LA, Wright PM, Guernieri RL, Brown JL, Skerry JC. Webb RP, et al. Among authors: smith tj, smith la. Toxins (Basel). 2017 Sep 3;9(9):269. doi: 10.3390/toxins9090269. Toxins (Basel). 2017. PMID: 28869522 Free PMC article.

2

Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins.

Webb RP, Smith TJ, Wright PM, Montgomery VA, Meagher MM, Smith LA. Webb RP, et al. Among authors: smith tj, smith la. Vaccine. 2007 May 22;25(21):4273-82. doi: 10.1016/j.vaccine.2007.02.081. Epub 2007 Mar 16. Vaccine. 2007. PMID: 17395341

3

Production of catalytically inactive BoNT/A1 holoprotein and comparison with BoNT/A1 subunit vaccines against toxin subtypes A1, A2, and A3.

Webb RP, Smith TJ, Wright P, Brown J, Smith LA. Webb RP, et al. Among authors: smith tj, smith la. Vaccine. 2009 Jul 16;27(33):4490-7. doi: 10.1016/j.vaccine.2009.05.030. Epub 2009 May 28. Vaccine. 2009. PMID: 19450643

4

What next for botulism vaccine development?

Webb RP, Smith LA. Webb RP, et al. Among authors: smith la. Expert Rev Vaccines. 2013 May;12(5):481-92. doi: 10.1586/erv.13.37. Expert Rev Vaccines. 2013. PMID: 23659297 Review.

5

Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.

Fan Y, Dong J, Lou J, Wen W, Conrad F, Geren IN, Garcia-Rodriguez C, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD. Fan Y, et al. Among authors: smith tj, smith la. Toxins (Basel). 2015 Aug 26;7(9):3405-23. doi: 10.3390/toxins7093405. Toxins (Basel). 2015. PMID: 26343720 Free PMC article.

6

Characterization of Hemagglutinin Negative Botulinum Progenitor Toxins.

Kalb SR, Baudys J, Smith TJ, Smith LA, Barr JR. Kalb SR, et al. Among authors: smith tj, smith la. Toxins (Basel). 2017 Jun 15;9(6):193. doi: 10.3390/toxins9060193. Toxins (Basel). 2017. PMID: 28617306 Free PMC article.

7

A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A.

Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD. Lou J, et al. Among authors: smith tj, smith la. Toxins (Basel). 2018 Feb 15;10(2):84. doi: 10.3390/toxins10020084. Toxins (Basel). 2018. PMID: 29462889 Free PMC article.

8

A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.

Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. Garcia-Rodriguez C, et al. Among authors: smith tj, smith la. Toxins (Basel). 2018 Mar 1;10(3):105. doi: 10.3390/toxins10030105. Toxins (Basel). 2018. PMID: 29494481 Free PMC article.

9

Potency and stability of a trivalent, catalytically inactive vaccine against botulinum neurotoxin serotypes C, E and F (triCEF).

Webb R, Wright PM, Brown JL, Skerry JC, Guernieri RL, Smith TJ, Stawicki C, Smith LA. Webb R, et al. Among authors: smith tj, smith la. Toxicon. 2020 Mar;176:67-76. doi: 10.1016/j.toxicon.2020.02.001. Epub 2020 Feb 4. Toxicon. 2020. PMID: 32032587

10

A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D.

Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. Garcia-Rodriguez C, et al. Among authors: smith tj, smith la. Toxins (Basel). 2021 Sep 10;13(9):641. doi: 10.3390/toxins13090641. Toxins (Basel). 2021. PMID: 34564645 Free PMC article.

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