Smith LA - Search Results

1

Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A.

Yalamanchili C, Manda VK, Chittiboyina AG, Guernieri RL, Harrell WA Jr, Webb RP, Smith LA, Khan IA. Yalamanchili C, et al. Among authors: smith la. J Ethnopharmacol. 2017 Feb 2;197:211-217. doi: 10.1016/j.jep.2016.07.069. Epub 2016 Jul 26. J Ethnopharmacol. 2017. PMID: 27469199

2

A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A.

Harrell WA Jr, Vieira RC, Ensel SM, Montgomery V, Guernieri R, Eccard VS, Campbell Y, Roxas-Duncan V, Cardellina JH 2nd, Webb RP, Smith LA. Harrell WA Jr, et al. Among authors: smith la. Bioorg Med Chem Lett. 2017 Feb 1;27(3):675-678. doi: 10.1016/j.bmcl.2016.11.019. Epub 2016 Nov 9. Bioorg Med Chem Lett. 2017. PMID: 28043798

3

What next for botulism vaccine development?

Webb RP, Smith LA. Webb RP, et al. Among authors: smith la. Expert Rev Vaccines. 2013 May;12(5):481-92. doi: 10.1586/erv.13.37. Expert Rev Vaccines. 2013. PMID: 23659297 Review.

4

Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism.

Webb RP, Smith TJ, Smith LA, Wright PM, Guernieri RL, Brown JL, Skerry JC. Webb RP, et al. Among authors: smith tj, smith la. Toxins (Basel). 2017 Sep 3;9(9):269. doi: 10.3390/toxins9090269. Toxins (Basel). 2017. PMID: 28869522 Free PMC article.

5

Potency and stability of a trivalent, catalytically inactive vaccine against botulinum neurotoxin serotypes C, E and F (triCEF).

Webb R, Wright PM, Brown JL, Skerry JC, Guernieri RL, Smith TJ, Stawicki C, Smith LA. Webb R, et al. Among authors: smith tj, smith la. Toxicon. 2020 Mar;176:67-76. doi: 10.1016/j.toxicon.2020.02.001. Epub 2020 Feb 4. Toxicon. 2020. PMID: 32032587

6

Production of catalytically inactive BoNT/A1 holoprotein and comparison with BoNT/A1 subunit vaccines against toxin subtypes A1, A2, and A3.

Webb RP, Smith TJ, Wright P, Brown J, Smith LA. Webb RP, et al. Among authors: smith tj, smith la. Vaccine. 2009 Jul 16;27(33):4490-7. doi: 10.1016/j.vaccine.2009.05.030. Epub 2009 May 28. Vaccine. 2009. PMID: 19450643

7

The C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active site.

Mizanur RM, Frasca V, Swaminathan S, Bavari S, Webb R, Smith LA, Ahmed SA. Mizanur RM, et al. Among authors: smith la. J Biol Chem. 2013 Aug 16;288(33):24223-33. doi: 10.1074/jbc.M113.451286. Epub 2013 Jun 18. J Biol Chem. 2013. PMID: 23779108 Free PMC article.

8

Protection with recombinant Clostridium botulinum C1 and D binding domain subunit (Hc) vaccines against C and D neurotoxins.

Webb RP, Smith TJ, Wright PM, Montgomery VA, Meagher MM, Smith LA. Webb RP, et al. Among authors: smith tj, smith la. Vaccine. 2007 May 22;25(21):4273-82. doi: 10.1016/j.vaccine.2007.02.081. Epub 2007 Mar 16. Vaccine. 2007. PMID: 17395341

9

Development of an o-pthalaldehyde (OPA) assay to measure protein content in Ricin Vaccine E. coli (RVEc™).

Montgomery VA, Lindsey CY, Smith LA, Webb RP. Montgomery VA, et al. Among authors: smith la. Vaccine. 2021 Jan 15;39(3):564-570. doi: 10.1016/j.vaccine.2020.12.008. Epub 2020 Dec 16. Vaccine. 2021. PMID: 33339670 Free article.

10

Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5.

Kalb SR, Baudys J, Webb RP, Wright P, Smith TJ, Smith LA, Fernández R, Raphael BH, Maslanka SE, Pirkle JL, Barr JR. Kalb SR, et al. Among authors: smith tj, smith la. FEBS Lett. 2012 Jan 20;586(2):109-15. doi: 10.1016/j.febslet.2011.11.033. Epub 2011 Dec 9. FEBS Lett. 2012. PMID: 22172278 Free PMC article.

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