Smith JM - Search Results

1

RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria.

Tu M, Tan VP, Yu JD, Tripathi R, Bigham Z, Barlow M, Smith JM, Brown JH, Miyamoto S. Tu M, et al. Among authors: smith jm. Cell Death Differ. 2022 Dec;29(12):2472-2486. doi: 10.1038/s41418-022-01032-w. Epub 2022 Jun 27. Cell Death Differ. 2022. PMID: 35760846 Free PMC article.

2

Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression.

Radeff-Huang J, Seasholtz TM, Chang JW, Smith JM, Walsh CT, Brown JH. Radeff-Huang J, et al. Among authors: smith jm. J Biol Chem. 2007 Jan 12;282(2):863-70. doi: 10.1074/jbc.M601698200. Epub 2006 Nov 19. J Biol Chem. 2007. PMID: 17114809 Free article.

3

PHLPP-1 negatively regulates Akt activity and survival in the heart.

Miyamoto S, Purcell NH, Smith JM, Gao T, Whittaker R, Huang K, Castillo R, Glembotski CC, Sussman MA, Newton AC, Brown JH. Miyamoto S, et al. Among authors: smith jm. Circ Res. 2010 Aug 20;107(4):476-84. doi: 10.1161/CIRCRESAHA.109.215020. Epub 2010 Jun 24. Circ Res. 2010. PMID: 20576936 Free PMC article.

4

Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes.

Roberts DJ, Tan-Sah VP, Smith JM, Miyamoto S. Roberts DJ, et al. Among authors: smith jm. J Biol Chem. 2013 Aug 16;288(33):23798-806. doi: 10.1074/jbc.M113.482026. Epub 2013 Jul 8. J Biol Chem. 2013. PMID: 23836898 Free PMC article.

5

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition.

Roberts DJ, Tan-Sah VP, Ding EY, Smith JM, Miyamoto S. Roberts DJ, et al. Among authors: smith jm. Mol Cell. 2014 Feb 20;53(4):521-33. doi: 10.1016/j.molcel.2013.12.019. Epub 2014 Jan 23. Mol Cell. 2014. PMID: 24462113 Free PMC article.

6

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity.

Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. Yu OM, et al. Oncogene. 2018 Oct;37(41):5492-5507. doi: 10.1038/s41388-018-0301-5. Epub 2018 Jun 11. Oncogene. 2018. PMID: 29887596 Free PMC article.

7

Dissociation of mitochondrial HK-II elicits mitophagy and confers cardioprotection against ischemia.

Tan VP, Smith JM, Tu M, Yu JD, Ding EY, Miyamoto S. Tan VP, et al. Among authors: smith jm. Cell Death Dis. 2019 Sep 30;10(10):730. doi: 10.1038/s41419-019-1965-7. Cell Death Dis. 2019. PMID: 31570704 Free PMC article.

8

Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion.

Chaim OM, Miki S, Prager BC, Ma J, Jeong AY, Lara J, Tran NK, Smith JM, Rich JN, Gutkind JS, Miyamoto S, Furnari FB, Brown JH. Chaim OM, et al. Among authors: smith jm. Sci Rep. 2023 Dec 16;13(1):22412. doi: 10.1038/s41598-023-49164-4. Sci Rep. 2023. PMID: 38104152 Free PMC article.

9

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis.

Bustamante MF, Oliveira PG, Garcia-Carbonell R, Croft AP, Smith JM, Serrano RL, Sanchez-Lopez E, Liu X, Kisseleva T, Hay N, Buckley CD, Firestein GS, Murphy AN, Miyamoto S, Guma M. Bustamante MF, et al. Among authors: smith jm. Ann Rheum Dis. 2018 Nov;77(11):1636-1643. doi: 10.1136/annrheumdis-2018-213103. Epub 2018 Jul 30. Ann Rheum Dis. 2018. PMID: 30061164 Free PMC article.

10

Pain management on a trauma service: a crisis reveals opportunities.

Schaffer S, Bayat D, Biffl WL, Smith J, Schaffer KB, Dandan TH, Wang J, Snyder D, Nalick C, Dandan IS, Tominaga GT, Castelo MR. Schaffer S, et al. Trauma Surg Acute Care Open. 2022 Mar 24;7(1):e000862. doi: 10.1136/tsaco-2021-000862. eCollection 2022. Trauma Surg Acute Care Open. 2022. PMID: 35402732 Free PMC article.

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