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Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin.
Song L, Zhang Y, Yun NE, Poussard AL, Smith JN, Smith JK, Borisevich V, Linde JJ, Zacks MA, Li H, Kavita U, Reiserova L, Liu X, Dumuren K, Balasubramanian B, Weaver B, Parent J, Umlauf S, Liu G, Huleatt J, Tussey L, Paessler S. Song L, et al. Among authors: smith jk, smith jn. Vaccine. 2009 Sep 25;27(42):5875-84. doi: 10.1016/j.vaccine.2009.07.060. Epub 2009 Aug 3. Vaccine. 2009. PMID: 19654064 Free PMC article.
Functional interferon system is required for clearance of lassa virus.
Yun NE, Poussard AL, Seregin AV, Walker AG, Smith JK, Aronson JF, Smith JN, Soong L, Paessler S. Yun NE, et al. Among authors: smith jk, smith jn. J Virol. 2012 Mar;86(6):3389-92. doi: 10.1128/JVI.06284-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238311 Free PMC article.
The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.
Seregin AV, Yun NE, Miller M, Aronson J, Smith JK, Walker AG, Smith JN, Huang C, Manning JT, de la Torre JC, Paessler S. Seregin AV, et al. Among authors: smith jk, smith jn. J Virol. 2015 Jun;89(11):5949-56. doi: 10.1128/JVI.00104-15. Epub 2015 Mar 25. J Virol. 2015. PMID: 25810546 Free PMC article.
Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus.
Yun NE, Seregin AV, Walker DH, Popov VL, Walker AG, Smith JN, Miller M, de la Torre JC, Smith JK, Borisevich V, Fair JN, Wauquier N, Grant DS, Bockarie B, Bente D, Paessler S. Yun NE, et al. Among authors: smith jk, smith jn. J Virol. 2013 Oct;87(19):10908-11. doi: 10.1128/JVI.01433-13. Epub 2013 Jul 31. J Virol. 2013. PMID: 23903830 Free PMC article.
RIG-I enhanced interferon independent apoptosis upon Junin virus infection.
Kolokoltsova OA, Grant AM, Huang C, Smith JK, Poussard AL, Tian B, Brasier AR, Peters CJ, Tseng CT, de la Torre JC, Paessler S. Kolokoltsova OA, et al. Among authors: smith jk. PLoS One. 2014 Jun 11;9(6):e99610. doi: 10.1371/journal.pone.0099610. eCollection 2014. PLoS One. 2014. PMID: 24918927 Free PMC article.
547 results