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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer.
Achinger-Kawecka J, Valdes-Mora F, Luu PL, Giles KA, Caldon CE, Qu W, Nair S, Soto S, Locke WJ, Yeo-Teh NS, Gould CM, Du Q, Smith GC, Ramos IR, Fernandez KF, Hoon DS, Gee JMW, Stirzaker C, Clark SJ. Achinger-Kawecka J, et al. Among authors: smith gc. Nat Commun. 2020 Jan 16;11(1):320. doi: 10.1038/s41467-019-14098-x. Nat Commun. 2020. PMID: 31949157 Free PMC article.
DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns.
Skvortsova K, Masle-Farquhar E, Luu PL, Song JZ, Qu W, Zotenko E, Gould CM, Du Q, Peters TJ, Colino-Sanguino Y, Pidsley R, Nair SS, Khoury A, Smith GC, Miosge LA, Reed JH, Kench JG, Rubin MA, Horvath L, Bogdanovic O, Lim SM, Polo JM, Goodnow CC, Stirzaker C, Clark SJ. Skvortsova K, et al. Among authors: smith gc. Cancer Cell. 2019 Feb 11;35(2):297-314.e8. doi: 10.1016/j.ccell.2019.01.004. Cancer Cell. 2019. PMID: 30753827 Free article.
DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity.
Du Q, Smith GC, Luu PL, Ferguson JM, Armstrong NJ, Caldon CE, Campbell EM, Nair SS, Zotenko E, Gould CM, Buckley M, Chia KM, Portman N, Lim E, Kaczorowski D, Chan CL, Barton K, Deveson IW, Smith MA, Powell JE, Skvortsova K, Stirzaker C, Achinger-Kawecka J, Clark SJ. Du Q, et al. Among authors: smith gc, smith ma. Cell Rep. 2021 Sep 21;36(12):109722. doi: 10.1016/j.celrep.2021.109722. Cell Rep. 2021. PMID: 34551299 Free article.
A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation.
Colino-Sanguino Y, Cornett EM, Moulder D, Smith GC, Hrit J, Cordeiro-Spinetti E, Vaughan RM, Krajewski K, Rothbart SB, Clark SJ, Valdés-Mora F. Colino-Sanguino Y, et al. Among authors: smith gc. iScience. 2019 Nov 22;21:773-788. doi: 10.1016/j.isci.2019.10.053. Epub 2019 Oct 31. iScience. 2019. PMID: 31727574 Free PMC article.
Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin.
Fernando M, Lee S, Wark JR, Xiao D, Lim BY, O'Hara-Wright M, Kim HJ, Smith GC, Wong T, Teber ET, Ali RR, Yang P, Graham ME, Gonzalez-Cordero A. Fernando M, et al. Among authors: smith gc. Stem Cell Reports. 2022 Jun 14;17(6):1476-1492. doi: 10.1016/j.stemcr.2022.04.003. Epub 2022 May 5. Stem Cell Reports. 2022. PMID: 35523177 Free PMC article.
1,115 results