Smith GC - Search Results

1

Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1.

Du X, Zhang Y, Jo SR, Liu X, Qi Y, Osborne B, Byrne FL, Smith GC, Turner N, Hoehn KL, Brown AJ, Yang H. Du X, et al. Among authors: smith gc. Biochem J. 2015 Oct 15;471(2):243-53. doi: 10.1042/BJ20150602. Epub 2015 Aug 17. Biochem J. 2015. PMID: 26283546

2

Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling.

Chowdhury MK, Wu LE, Coleman JL, Smith NJ, Morris MJ, Shepherd PR, Smith GC. Chowdhury MK, et al. Among authors: smith nj, smith gc. Biochem J. 2016 May 1;473(9):1247-55. doi: 10.1042/BCJ20160121. Epub 2016 Mar 10. Biochem J. 2016. PMID: 26964897

3

Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes.

Chowdhury MK, Turner N, Bentley NL, Das A, Wu LE, Richani D, Bustamante S, Gilchrist RB, Morris MJ, Shepherd PR, Smith GC. Chowdhury MK, et al. Among authors: smith gc. Sci Rep. 2017 Jan 5;7:40159. doi: 10.1038/srep40159. Sci Rep. 2017. PMID: 28054648 Free PMC article.

4

FOX01 Is the Headline Akt Regulating Hepatic Glucose Metabolism.

Smith GC, Turner N. Smith GC, et al. Endocrinology. 2017 Aug 1;158(8):2436-2438. doi: 10.1210/en.2017-00525. Endocrinology. 2017. PMID: 28838141 No abstract available.

5

Defining lipid mediators of insulin resistance - controversies and challenges.

Metcalfe LK, Smith GC, Turner N. Metcalfe LK, et al. Among authors: smith gc. J Mol Endocrinol. 2018 Aug 1:JME-18-0023. doi: 10.1530/JME-18-0023. Online ahead of print. J Mol Endocrinol. 2018. PMID: 30068522

6

Limited Metabolic Effect of the CREBRF^R457Q Obesity Variant in Mice.

Metcalfe LK, Shepherd PR, Smith GC, Turner N. Metcalfe LK, et al. Among authors: smith gc. Cells. 2022 Jan 31;11(3):497. doi: 10.3390/cells11030497. Cells. 2022. PMID: 35159305 Free PMC article.

7

Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice.

Chen SY, Beretta M, Olzomer EM, Shah DP, Wong DYH, Alexopoulos SJ, Aleksovska I, Salamoun JM, Garcia CJ, Cochran BJ, Rye KA, Smith GC, Byrne FL, Morris MJ, Santos WL, Cantley J, Hoehn KL. Chen SY, et al. Among authors: smith gc. Mol Metab. 2023 Mar;69:101684. doi: 10.1016/j.molmet.2023.101684. Epub 2023 Jan 31. Mol Metab. 2023. PMID: 36731653 Free PMC article.

8

The Māori and Pacific specific CREBRF variant and adult height.

Metcalfe LK, Krishnan M, Turner N, Yaghootkar H, Merry TL, Dewes O, Hindmarsh JH, De Zoysa J, Dalbeth N, Stamp LK, Merriman TR, Smith G, Shepherd P, Murphy R. Metcalfe LK, et al. Int J Obes (Lond). 2020 Mar;44(3):748-752. doi: 10.1038/s41366-019-0437-6. Epub 2019 Sep 22. Int J Obes (Lond). 2020. PMID: 31543511

9

Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo.

Smith GC, Ong WK, Rewcastle GW, Kendall JD, Han W, Shepherd PR. Smith GC, et al. Biochem J. 2012 Feb 15;442(1):161-9. doi: 10.1042/BJ20111913. Biochem J. 2012. PMID: 22142257 Free PMC article.

10

Glucagon phosphorylates serine 552 of β-catenin leading to increased expression of cyclin D1 and c-Myc in the isolated rat liver.

Chowdhury MK, Montgomery MK, Morris MJ, Cognard E, Shepherd PR, Smith GC. Chowdhury MK, et al. Among authors: smith gc. Arch Physiol Biochem. 2015;121(3):88-96. doi: 10.3109/13813455.2015.1048693. Epub 2015 Jul 1. Arch Physiol Biochem. 2015. PMID: 26135564

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