Smith DM - Search Results

1

Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screening Reveals Small Molecules Targeting the CDK2/4-C/EBPα/DGAT2 Pathway Preventing ER-Stress Induced Lipid Accumulation.

Parafati M, Bae SH, Kirby RJ, Fitzek M, Iyer P, Engkvist O, Smith DM, Malany S. Parafati M, et al. Among authors: smith dm. Int J Mol Sci. 2020 Dec 15;21(24):9557. doi: 10.3390/ijms21249557. Int J Mol Sci. 2020. PMID: 33334026 Free PMC article.

2

Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition.

Brito H, Marques V, Afonso MB, Brown DG, Börjesson U, Selmi N, Smith DM, Roberts IO, Fitzek M, Aniceto N, Guedes RC, Moreira R, Rodrigues CMP. Brito H, et al. Among authors: smith dm. Cell Death Discov. 2020 Feb 11;6:6. doi: 10.1038/s41420-020-0240-0. eCollection 2020. Cell Death Discov. 2020. PMID: 32123582 Free PMC article.

3

A small molecule inhibitor of HER3: a proof-of-concept study.

Colomba A, Fitzek M, George R, Weitsman G, Roberts S, Zanetti-Domingues L, Hirsch M, Rolfe DJ, Mehmood S, Madin A, Claus J, Kjaer S, Snijders AP, Ng T, Martin-Fernandez M, Smith DM, Parker PJ. Colomba A, et al. Among authors: smith dm. Biochem J. 2020 Sep 18;477(17):3329-3347. doi: 10.1042/BCJ20200496. Biochem J. 2020. PMID: 32815546 Free PMC article.

4

Fragment-Based Screening Identifies New Quinazolinone-Based Inositol Hexakisphosphate Kinase (IP6K) Inhibitors.

Heitmann T, Liao G, de León P, Ernst G, Buchler I, Wei H, Shlevkov E, Brown D, Fitzek M, Collier M, Smith DM, Barrow JC. Heitmann T, et al. Among authors: smith dm. ACS Med Chem Lett. 2023 Nov 28;14(12):1760-1766. doi: 10.1021/acsmedchemlett.3c00409. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116421

5

Identification of epidermal growth factor receptor-tyrosine kinase inhibitor targeting the VP1 pocket of human rhinovirus.

Miah M, Davis AM, Hannoun C, Said JS, Fitzek M, Preston M, Smith D, Uwamariya C, Kärmander A, Lundbäck T, Bergström T, Trybala E. Miah M, et al. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0106423. doi: 10.1128/aac.01064-23. Epub 2024 Feb 13. Antimicrob Agents Chemother. 2024. PMID: 38349161 Free PMC article.

6

A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets.

Mullooly N, Smith DM, Gianni D. Mullooly N, et al. Among authors: smith dm. SLAS Discov. 2023 Mar;28(2):3-12. doi: 10.1016/j.slasd.2023.01.002. Epub 2023 Jan 13. SLAS Discov. 2023. PMID: 36646173 Free article.

7

The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326.

Ford BE, Chachra SS, Rodgers K, Moonira T, Al-Oanzi ZH, Anstee QM, Reeves HL, Schattenberg JM, Fairclough RJ, Smith DM, Tiniakos D, Agius L. Ford BE, et al. Among authors: smith dm. Mol Metab. 2023 Jun;72:101722. doi: 10.1016/j.molmet.2023.101722. Epub 2023 Apr 7. Mol Metab. 2023. PMID: 37031802 Free PMC article.

8

AMP-activated protein kinase activation suppresses leptin expression independently of adipogenesis in primary murine adipocytes.

Bustraan S, Bennett J, Whilding C, Pennycook BR, Smith D, Barr AR, Read J, Carling D, Pollard A. Bustraan S, et al. Biochem J. 2024 Mar 6;481(5):345-362. doi: 10.1042/BCJ20240003. Biochem J. 2024. PMID: 38314646 Free PMC article.

9

Safety, Efficacy, and Pharmacokinetics of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies BMS-986414 (C135-LS) and BMS-986413 (C144-LS) Administered Subcutaneously in Non-Hospitalized Persons with COVID-19 in a Phase 2 Trial.

Corado KC, Chew KW, Giganti MJ, Mu Y, Fletcher CV, Currier JS, Daar ES, Wohl DA, Li JZ, Moser CB, Ritz J, Javan AC, Neytman G, Caskey M, Hughes MD, Smith DM, Eron JJ; ACTIV-2/A5401 Study Team. Corado KC, et al. Among authors: smith dm. Pathog Immun. 2024 May 6;9(1):138-155. doi: 10.20411/pai.v9i1.660. eCollection 2024. Pathog Immun. 2024. PMID: 38746756 Free PMC article.

10

Risk Analysis of Respiratory Syncytial Virus Among Infants in the United States by Birth Month.

Gantenberg JR, van Aalst R, Reddy Bhuma M, Limone B, Diakun D, Smith DM, Nelson CB, Bengtson AM, Chaves SS, La Via WV, Rizzo C, Savitz DA, Zullo AR. Gantenberg JR, et al. Among authors: smith dm. J Pediatric Infect Dis Soc. 2024 May 13:piae042. doi: 10.1093/jpids/piae042. Online ahead of print. J Pediatric Infect Dis Soc. 2024. PMID: 38738450

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,799 results

Search Page