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Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma.
Havas AP, Rodrigues KB, Bhakta A, Demirjian JA, Hahn S, Tran J, Scavello M, Tula-Sanchez AA, Zeng Y, Schmelz M, Smith CL. Havas AP, et al. Among authors: smith cl. Cancer Biol Ther. 2016 Dec;17(12):1240-1252. doi: 10.1080/15384047.2016.1250046. Epub 2016 Oct 28. Cancer Biol Ther. 2016. PMID: 27791595 Free PMC article.
Defining cellular responses to HDAC-selective inhibitors reveals that efficient targeting of HDAC3 is required to elicit cytotoxicity and overcome naïve resistance to pan-HDACi in diffuse large B cell lymphoma.
Havas AP, Tula-Sanchez AA, Steenhoek HM, Bhakta A, Wingfield T, Huntley MJ, Nofal AS, Ahmed T, Jaime-Frias R, Smith CL. Havas AP, et al. Among authors: smith cl. Transl Oncol. 2024 Jan;39:101779. doi: 10.1016/j.tranon.2023.101779. Epub 2023 Oct 20. Transl Oncol. 2024. PMID: 37865047 Free PMC article.
1,070 results