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Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
Tzioras M, Daniels MJD, Davies C, Baxter P, King D, McKay S, Varga B, Popovic K, Hernandez M, Stevenson AJ, Barrington J, Drinkwater E, Borella J, Holloway RK, Tulloch J, Moss J, Latta C, Kandasamy J, Sokol D, Smith C, Miron VE, Káradóttir RT, Hardingham GE, Henstridge CM, Brennan PM, McColl BW, Spires-Jones TL. Tzioras M, et al. Among authors: smith c. Cell Rep Med. 2023 Sep 19;4(9):101175. doi: 10.1016/j.xcrm.2023.101175. Epub 2023 Aug 30. Cell Rep Med. 2023. PMID: 37652017 Free PMC article.
Activin receptors regulate the oligodendrocyte lineage in health and disease.
Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH, Becher JC, Smith C, Williams A, Miron VE. Dillenburg A, et al. Among authors: smith c. Acta Neuropathol. 2018 Jun;135(6):887-906. doi: 10.1007/s00401-018-1813-3. Epub 2018 Feb 3. Acta Neuropathol. 2018. PMID: 29397421 Free PMC article.
Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
Askew KE, Beverley J, Sigfridsson E, Szymkowiak S, Emelianova K, Dando O, Hardingham GE, Duncombe J, Hennessy E, Koudelka J, Samarasekera N, Salman RA, Smith C, Tavares AAS, Gomez-Nicola D, Kalaria RN, McColl BW, Horsburgh K. Askew KE, et al. Among authors: smith c. Glia. 2024 Feb;72(2):375-395. doi: 10.1002/glia.24481. Epub 2023 Nov 1. Glia. 2024. PMID: 37909242 Free PMC article.
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.
Sri S, Greenstein A, Granata A, Collcutt A, Jochems ACC, McColl BW, Castro BD, Webber C, Reyes CA, Hall C, Lawrence CB, Hawkes C, Pegasiou-Davies CM, Gibson C, Crawford CL, Smith C, Vivien D, McLean FH, Wiseman F, Brezzo G, Lalli G, Pritchard HAT, Markus HS, Bravo-Ferrer I, Taylor J, Leiper J, Berwick J, Gan J, Gallacher J, Moss J, Goense J, McMullan L, Work L, Evans L, Stringer MS, Ashford M, Abulfadl M, Conlon N, Malhotra P, Bath P, Canter R, Brown R, Ince S, Anderle S, Young S, Quick S, Szymkowiak S, Hill S, Allan S, Wang T, Quinn T, Procter T, Farr TD, Zhao X, Yang Z, Hainsworth AH, Wardlaw JM. Sri S, et al. Among authors: smith c. Cereb Circ Cogn Behav. 2023 Oct 11;5:100189. doi: 10.1016/j.cccb.2023.100189. eCollection 2023. Cereb Circ Cogn Behav. 2023. PMID: 37941765 Free PMC article. Review.
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, Jackson RJ, Catterson JH, Spires-Jones MP, Rose J, Waybright L, Caggiano AO, King D, Gobbo F, Davies C, Hooley M, Dunnett S, Tempelaar R, Meftah S, Tzioras M, Hamby ME, Izzo NJ, Catalano SM, Durrant CS, Smith C, Dando O, Spires-Jones TL. Colom-Cadena M, et al. Among authors: smith c. Acta Neuropathol. 2024 Feb 6;147(1):32. doi: 10.1007/s00401-023-02679-6. Acta Neuropathol. 2024. PMID: 38319380 Free PMC article.
Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae.
Albayram O, Kondo A, Mannix R, Smith C, Tsai CY, Li C, Herbert MK, Qiu J, Monuteaux M, Driver J, Yan S, Gormley W, Puccio AM, Okonkwo DO, Lucke-Wold B, Bailes J, Meehan W, Zeidel M, Lu KP, Zhou XZ. Albayram O, et al. Among authors: smith c. Nat Commun. 2017 Oct 17;8(1):1000. doi: 10.1038/s41467-017-01068-4. Nat Commun. 2017. PMID: 29042562 Free PMC article.
Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial.
Goodyear CS, Patel A, Barnes E, Willicombe M, Siebert S, de Silva TI, Snowden JA, Lim SH, Bowden SJ, Billingham L, Richter A, Carroll M, Carr EJ, Beale R, Rea D, Parry H, Pirrie S, Lim Z, Satsangi J, Dunachie SJ, Cook G, Miller P, Basu N, Gilmour A, Hodgkins AM, Evans L, Hughes A, Longet S, Meacham G, Yong KL, A'Hearne MJ, Koh MBC, Burns SO, Orchard K, Paterson C, McIlroy G, Murray SM, Thomson T, Dimitriadis S, Goulston L, Miller S, Keillor V, Prendecki M, Thomas D, Kirkham A, McInnes IB, Kearns P; OCTAVE-DUO investigators. Goodyear CS, et al. Lancet Rheumatol. 2024 May 8:S2665-9913(24)00065-1. doi: 10.1016/S2665-9913(24)00065-1. Online ahead of print. Lancet Rheumatol. 2024. PMID: 38734019
Improving Prostate MR Image Quality in Practice - Initial results from the ACR Prostate MR Image Quality Improvement Collaborative.
Purysko AS, Zacharias-Andrews K, Tomkins KG, Turkbey IB, Giganti F, Bhargavan-Chatfield M, Larson DB; ACR Prostate MR Image Quality Improvement Collaborative. Purysko AS, et al. J Am Coll Radiol. 2024 May 8:S1546-1440(24)00416-2. doi: 10.1016/j.jacr.2024.04.008. Online ahead of print. J Am Coll Radiol. 2024. PMID: 38729590
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