Smith BJ - Search Results

1

Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA.

Khoo KK, Wilson MJ, Smith BJ, Zhang MM, Gulyas J, Yoshikami D, Rivier JE, Bulaj G, Norton RS. Khoo KK, et al. Among authors: smith bj. J Med Chem. 2011 Nov 10;54(21):7558-66. doi: 10.1021/jm200839a. Epub 2011 Oct 12. J Med Chem. 2011. PMID: 21962108 Free PMC article.

2

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, Terlau H, McArthur JR, French RJ, Gulyas J, Rivier JE, Smith BJ, Norton RS, Olivera BM, Yoshikami D, Bulaj G. Zhang MM, et al. Among authors: smith bj. J Biol Chem. 2007 Oct 19;282(42):30699-706. doi: 10.1074/jbc.M704616200. Epub 2007 Aug 27. J Biol Chem. 2007. PMID: 17724025 Free article.

3

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion.

Khoo KK, Feng ZP, Smith BJ, Zhang MM, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Khoo KK, et al. Among authors: smith bj. Biochemistry. 2009 Feb 17;48(6):1210-9. doi: 10.1021/bi801998a. Biochemistry. 2009. PMID: 19170536 Free PMC article.

4

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity.

Green BR, Catlin P, Zhang MM, Fiedler B, Bayudan W, Morrison A, Norton RS, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Green BR, et al. Among authors: smith bj. Chem Biol. 2007 Apr;14(4):399-407. doi: 10.1016/j.chembiol.2007.02.009. Chem Biol. 2007. PMID: 17462575

5

N-Terminally extended analogues of the K⁺ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage-gated potassium channel Kv1.3.

Chang SC, Huq R, Chhabra S, Beeton C, Pennington MW, Smith BJ, Norton RS. Chang SC, et al. Among authors: smith bj. FEBS J. 2015 Jun;282(12):2247-59. doi: 10.1111/febs.13294. Epub 2015 Apr 23. FEBS J. 2015. PMID: 25864722 Free PMC article.

6

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

Bulaj G, West PJ, Garrett JE, Watkins M, Zhang MM, Norton RS, Smith BJ, Yoshikami D, Olivera BM. Bulaj G, et al. Among authors: smith bj. Biochemistry. 2005 May 17;44(19):7259-65. doi: 10.1021/bi0473408. Biochemistry. 2005. PMID: 15882064

7

Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking.

Galea CA, Nguyen HM, George Chandy K, Smith BJ, Norton RS. Galea CA, et al. Among authors: smith bj. Cell Mol Life Sci. 2014 Apr;71(7):1191-210. doi: 10.1007/s00018-013-1431-0. Epub 2013 Aug 3. Cell Mol Life Sci. 2014. PMID: 23912897 Review.

8

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.

Menting JG, Gajewiak J, MacRaild CA, Chou DH, Disotuar MM, Smith NA, Miller C, Erchegyi J, Rivier JE, Olivera BM, Forbes BE, Smith BJ, Norton RS, Safavi-Hemami H, Lawrence MC. Menting JG, et al. Among authors: smith bj, smith na. Nat Struct Mol Biol. 2016 Oct;23(10):916-920. doi: 10.1038/nsmb.3292. Epub 2016 Sep 12. Nat Struct Mol Biol. 2016. PMID: 27617429

9

Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the Campylobacter jejuni Chemoreceptor Tlp3.

Khan MF, Machuca MA, Rahman MM, Koç C, Norton RS, Smith BJ, Roujeinikova A. Khan MF, et al. Among authors: smith bj. Biomolecules. 2020 May 11;10(5):744. doi: 10.3390/biom10050744. Biomolecules. 2020. PMID: 32403336 Free PMC article.

10

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Zhang MM, et al. Among authors: smith bj. Biochemistry. 2006 Mar 21;45(11):3723-32. doi: 10.1021/bi052162j. Biochemistry. 2006. PMID: 16533055

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