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Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types.
Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC. Jones Lipinski RA, et al. Among authors: smith bc. Am J Physiol Regul Integr Comp Physiol. 2024 Apr 15. doi: 10.1152/ajpregu.00259.2023. Online ahead of print. Am J Physiol Regul Integr Comp Physiol. 2024. PMID: 38618911
Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.
Fisher CL, Pavan M, Salmaso V, Keyes RF, Wan TC, Pradhan B, Gao ZG, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: smith bc. Mol Pharmacol. 2024 Feb 15;105(3):213-223. doi: 10.1124/molpharm.123.000784. Mol Pharmacol. 2024. PMID: 38182432 Free PMC article.
308 results