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Characterization of Dual-Acting A3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gαi3 and GαoA Isoprotein Activation.
Fisher CL, Fallot LB, Wan TC, Keyes RF, Suresh RR, Rothwell AC, Gao ZG, McCorvy JD, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: smith bc. ACS Pharmacol Transl Sci. 2022 Jul 15;5(8):625-641. doi: 10.1021/acsptsci.2c00076. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983277 Free PMC article.
Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening.
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC. Shishodia S, et al. Among authors: smith bc. J Med Chem. 2022 Oct 27;65(20):13714-13735. doi: 10.1021/acs.jmedchem.2c00864. Epub 2022 Oct 13. J Med Chem. 2022. PMID: 36227159 Free PMC article.
308 results