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The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates.
Kennan RM, Wong W, Dhungyel OP, Han X, Wong D, Parker D, Rosado CJ, Law RH, McGowan S, Reeve SB, Levina V, Powers GA, Pike RN, Bottomley SP, Smith AI, Marsh I, Whittington RJ, Whisstock JC, Porter CJ, Rood JI. Kennan RM, et al. Among authors: smith ai. PLoS Pathog. 2010 Nov 24;6(11):e1001210. doi: 10.1371/journal.ppat.1001210. PLoS Pathog. 2010. PMID: 21124876 Free PMC article.
The NEAT Domain-Containing Proteins of Clostridium perfringens Bind Heme.
Choo JM, Cheung JK, Wisniewski JA, Steer DL, Bulach DM, Hiscox TJ, Chakravorty A, Smith AI, Gell DA, Rood JI, Awad MM. Choo JM, et al. Among authors: smith ai. PLoS One. 2016 Sep 16;11(9):e0162981. doi: 10.1371/journal.pone.0162981. eCollection 2016. PLoS One. 2016. PMID: 27637108 Free PMC article.
The X-ray crystal structure of full-length human plasminogen.
Law RH, Caradoc-Davies T, Cowieson N, Horvath AJ, Quek AJ, Encarnacao JA, Steer D, Cowan A, Zhang Q, Lu BG, Pike RN, Smith AI, Coughlin PB, Whisstock JC. Law RH, et al. Among authors: smith ai. Cell Rep. 2012 Mar 29;1(3):185-90. doi: 10.1016/j.celrep.2012.02.012. Epub 2012 Mar 8. Cell Rep. 2012. PMID: 22832192 Free article.
The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.
Yongqing T, Wilmann PG, Reeve SB, Coetzer TH, Smith AI, Whisstock JC, Pike RN, Wijeyewickrema LC. Yongqing T, et al. Among authors: smith ai. J Biol Chem. 2013 Aug 2;288(31):22399-407. doi: 10.1074/jbc.M113.483875. Epub 2013 Jun 21. J Biol Chem. 2013. PMID: 23792966 Free PMC article.
X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
McGowan S, Buckle AM, Irving JA, Ong PC, Bashtannyk-Puhalovich TA, Kan WT, Henderson KN, Bulynko YA, Popova EY, Smith AI, Bottomley SP, Rossjohn J, Grigoryev SA, Pike RN, Whisstock JC. McGowan S, et al. Among authors: smith ai. EMBO J. 2006 Jul 12;25(13):3144-55. doi: 10.1038/sj.emboj.7601201. Epub 2006 Jun 29. EMBO J. 2006. PMID: 16810322 Free PMC article.
236 results