Smit L - Search Results

1

LKB1 tumor suppressor protein: PARtaker in cell polarity.

Baas AF, Smit L, Clevers H. Baas AF, et al. Among authors: smit l. Trends Cell Biol. 2004 Jun;14(6):312-9. doi: 10.1016/j.tcb.2004.04.001. Trends Cell Biol. 2004. PMID: 15183188 Review.

2

Wnt activates the Tak1/Nemo-like kinase pathway.

Smit L, Baas A, Kuipers J, Korswagen H, van de Wetering M, Clevers H. Smit L, et al. J Biol Chem. 2004 Apr 23;279(17):17232-40. doi: 10.1074/jbc.M307801200. Epub 2004 Feb 11. J Biol Chem. 2004. PMID: 14960582 Free article.

3

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.

Baas AF, Boudeau J, Sapkota GP, Smit L, Medema R, Morrice NA, Alessi DR, Clevers HC. Baas AF, et al. Among authors: smit l. EMBO J. 2003 Jun 16;22(12):3062-72. doi: 10.1093/emboj/cdg292. EMBO J. 2003. PMID: 12805220 Free PMC article.

4

Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

Carretero J, Medina PP, Blanco R, Smit L, Tang M, Roncador G, Maestre L, Conde E, Lopez-Rios F, Clevers HC, Sanchez-Cespedes M. Carretero J, et al. Among authors: smit l. Oncogene. 2007 Mar 8;26(11):1616-25. doi: 10.1038/sj.onc.1209951. Epub 2006 Sep 4. Oncogene. 2007. PMID: 16953221

5

IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival.

Verhagen HJ, de Leeuw DC, Roemer MG, Denkers F, Pouwels W, Rutten A, Celie PH, Ossenkoppele GJ, Schuurhuis GJ, Smit L. Verhagen HJ, et al. Among authors: smit l. Cell Death Dis. 2014 Jun 26;5(6):e1300. doi: 10.1038/cddis.2014.268. Cell Death Dis. 2014. PMID: 24967962 Free PMC article.

6

An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation.

Smit L, Berns K, Spence K, Ryder WD, Zeps N, Madiredjo M, Beijersbergen R, Bernards R, Clarke RB. Smit L, et al. Oncotarget. 2016 Jan 19;7(3):2596-610. doi: 10.18632/oncotarget.6354. Oncotarget. 2016. PMID: 26595803 Free PMC article.

7

MicroRNA-551b is highly expressed in hematopoietic stem cells and a biomarker for relapse and poor prognosis in acute myeloid leukemia.

de Leeuw DC, Verhagen HJ, Denkers F, Kavelaars FG, Valk PJ, Schuurhuis GJ, Ossenkoppele GJ, Smit L. de Leeuw DC, et al. Among authors: smit l. Leukemia. 2016 Mar;30(3):742-6. doi: 10.1038/leu.2015.160. Epub 2015 Jun 25. Leukemia. 2016. PMID: 26108690 No abstract available.

8

MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia.

de Leeuw DC, van den Ancker W, Denkers F, de Menezes RX, Westers TM, Ossenkoppele GJ, van de Loosdrecht AA, Smit L. de Leeuw DC, et al. Among authors: smit l. Clin Cancer Res. 2013 Apr 15;19(8):2187-96. doi: 10.1158/1078-0432.CCR-12-3657. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444217

9

Attenuation of microRNA-126 expression that drives CD34+38- stem/progenitor cells in acute myeloid leukemia leads to tumor eradication.

de Leeuw DC, Denkers F, Olthof MC, Rutten AP, Pouwels W, Schuurhuis GJ, Ossenkoppele GJ, Smit L. de Leeuw DC, et al. Among authors: smit l. Cancer Res. 2014 Apr 1;74(7):2094-105. doi: 10.1158/0008-5472.CAN-13-1733. Epub 2014 Jan 29. Cancer Res. 2014. PMID: 24477595

10

Primary acute myeloid leukemia cells with overexpression of EVI-1 are sensitive to all-trans retinoic acid.

Verhagen HJ, Smit MA, Rutten A, Denkers F, Poddighe PJ, Merle PA, Ossenkoppele GJ, Smit L. Verhagen HJ, et al. Among authors: smit ma, smit l. Blood. 2016 Jan 28;127(4):458-63. doi: 10.1182/blood-2015-07-653840. Epub 2015 Nov 18. Blood. 2016. PMID: 26582376 Free article.

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