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Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood-brain barrier in mice.
Alhaddad H, Cisternino S, Declèves X, Tournier N, Schlatter J, Chiadmi F, Risède P, Smirnova M, Besengez C, Scherrmann JM, Baud FJ, Mégarbane B. Alhaddad H, et al. Among authors: smirnova m. Crit Care Med. 2012 Dec;40(12):3215-23. doi: 10.1097/CCM.0b013e318265680a. Crit Care Med. 2012. PMID: 22975888
Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties.
Seleman M, Chapy H, Cisternino S, Courtin C, Smirnova M, Schlatter J, Chiadmi F, Scherrmann JM, Noble F, Marie-Claire C. Seleman M, et al. Among authors: smirnova m. Psychopharmacology (Berl). 2014 Aug;231(16):3139-49. doi: 10.1007/s00213-014-3490-9. Epub 2014 Apr 5. Psychopharmacology (Berl). 2014. PMID: 24705903
Immune quiescence of the brain is set by astroglial connexin 43.
Boulay AC, Mazeraud A, Cisternino S, Saubaméa B, Mailly P, Jourdren L, Blugeon C, Mignon V, Smirnova M, Cavallo A, Ezan P, Avé P, Dingli F, Loew D, Vieira P, Chrétien F, Cohen-Salmon M. Boulay AC, et al. Among authors: smirnova m. J Neurosci. 2015 Mar 11;35(10):4427-39. doi: 10.1523/JNEUROSCI.2575-14.2015. J Neurosci. 2015. PMID: 25762685 Free PMC article.
Diphenhydramine as a selective probe to study H+-antiporter function at the blood-brain barrier: Application to [11C]diphenhydramine positron emission tomography imaging.
Auvity S, Chapy H, Goutal S, Caillé F, Hosten B, Smirnova M, Declèves X, Tournier N, Cisternino S. Auvity S, et al. Among authors: smirnova m. J Cereb Blood Flow Metab. 2017 Jun;37(6):2185-2195. doi: 10.1177/0271678X16662042. Epub 2016 Jan 1. J Cereb Blood Flow Metab. 2017. PMID: 27488910 Free PMC article.
Optimization and in Vivo Validation of Peptide Vectors Targeting the LDL Receptor.
Jacquot G, Lécorché P, Malcor JD, Laurencin M, Smirnova M, Varini K, Malicet C, Gassiot F, Abouzid K, Faucon A, David M, Gaudin N, Masse M, Ferracci G, Dive V, Cisternino S, Khrestchatisky M. Jacquot G, et al. Among authors: smirnova m. Mol Pharm. 2016 Dec 5;13(12):4094-4105. doi: 10.1021/acs.molpharmaceut.6b00687. Epub 2016 Oct 11. Mol Pharm. 2016. PMID: 27656777
294 results