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Metabolic protein kinase signalling in neuroblastoma.
Smiles WJ, Catalano L, Stefan VE, Weber DD, Kofler B. Smiles WJ, et al. Mol Metab. 2023 Sep;75:101771. doi: 10.1016/j.molmet.2023.101771. Epub 2023 Jul 4. Mol Metab. 2023. PMID: 37414143 Free PMC article. Review.
Triple Therapy with Metformin, Ketogenic Diet, and Metronomic Cyclophosphamide Reduced Tumor Growth in MYCN-Amplified Neuroblastoma Xenografts.
Catalano L, Aminzadeh-Gohari S, Weber DD, Poupardin R, Stefan VE, Smiles WJ, Tevini J, Feichtinger RG, Derdak S, Bilban M, Bareswill S, Heimesaat MM, Kofler B. Catalano L, et al. Among authors: smiles wj. Metabolites. 2023 Aug 3;13(8):910. doi: 10.3390/metabo13080910. Metabolites. 2023. PMID: 37623854 Free PMC article.
A novel small molecule inhibitor of human Drp1.
Rosdah AA, Abbott BM, Langendorf CG, Deng Y, Truong JQ, Waddell HMM, Ling NXY, Smiles WJ, Delbridge LMD, Liu GS, Oakhill JS, Lim SY, Holien JK. Rosdah AA, et al. Among authors: smiles wj. Sci Rep. 2022 Dec 13;12(1):21531. doi: 10.1038/s41598-022-25464-z. Sci Rep. 2022. PMID: 36513726 Free PMC article.
An AMPKα2-specific phospho-switch controls lysosomal targeting for activation.
Morrison KR, Smiles WJ, Ling NXY, Hoque A, Shea G, Ngoei KRW, Yu D, Murray-Segal L, Scott JW, Galic S, Kemp BE, Petersen J, Oakhill JS. Morrison KR, et al. Among authors: smiles wj. Cell Rep. 2022 Feb 15;38(7):110365. doi: 10.1016/j.celrep.2022.110365. Cell Rep. 2022. PMID: 35172150 Free article.
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms.
Pinkosky SL, Scott JW, Desjardins EM, Smith BK, Day EA, Ford RJ, Langendorf CG, Ling NXY, Nero TL, Loh K, Galic S, Hoque A, Smiles WJ, Ngoei KRW, Parker MW, Yan Y, Melcher K, Kemp BE, Oakhill JS, Steinberg GR. Pinkosky SL, et al. Among authors: smiles wj. Nat Metab. 2020 Sep;2(9):873-881. doi: 10.1038/s42255-020-0245-2. Epub 2020 Jul 27. Nat Metab. 2020. PMID: 32719536 Free PMC article.
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism.
Hoffman NJ, Whitfield J, Janzen NR, Belhaj MR, Galic S, Murray-Segal L, Smiles WJ, Ling NXY, Dite TA, Scott JW, Oakhill JS, Brink R, Kemp BE, Hawley JA. Hoffman NJ, et al. Among authors: smiles wj. Mol Metab. 2020 Nov;41:101048. doi: 10.1016/j.molmet.2020.101048. Epub 2020 Jun 29. Mol Metab. 2020. PMID: 32610071 Free PMC article.
27 results