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A genome-scale screen for synthetic drivers of T cell proliferation.
Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE. Legut M, et al. Among authors: smibert p. Nature. 2022 Mar;603(7902):728-735. doi: 10.1038/s41586-022-04494-7. Epub 2022 Mar 16. Nature. 2022. PMID: 35296855 Free PMC article.
Simultaneous epitope and transcriptome measurement in single cells.
Stoeckius M, Hafemeister C, Stephenson W, Houck-Loomis B, Chattopadhyay PK, Swerdlow H, Satija R, Smibert P. Stoeckius M, et al. Among authors: smibert p. Nat Methods. 2017 Sep;14(9):865-868. doi: 10.1038/nmeth.4380. Epub 2017 Jul 31. Nat Methods. 2017. PMID: 28759029 Free PMC article.
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens.
Liscovitch-Brauer N, Montalbano A, Deng J, Méndez-Mancilla A, Wessels HH, Moss NG, Kung CY, Sookdeo A, Guo X, Geller E, Jaini S, Smibert P, Sanjana NE. Liscovitch-Brauer N, et al. Among authors: smibert p. Nat Biotechnol. 2021 Oct;39(10):1270-1277. doi: 10.1038/s41587-021-00902-x. Epub 2021 Apr 29. Nat Biotechnol. 2021. PMID: 33927415 Free PMC article.
Integrated analysis of multimodal single-cell data.
Hao Y, Hao S, Andersen-Nissen E, Mauck WM 3rd, Zheng S, Butler A, Lee MJ, Wilk AJ, Darby C, Zager M, Hoffman P, Stoeckius M, Papalexi E, Mimitou EP, Jain J, Srivastava A, Stuart T, Fleming LM, Yeung B, Rogers AJ, McElrath JM, Blish CA, Gottardo R, Smibert P, Satija R. Hao Y, et al. Among authors: smibert p. Cell. 2021 Jun 24;184(13):3573-3587.e29. doi: 10.1016/j.cell.2021.04.048. Epub 2021 May 31. Cell. 2021. PMID: 34062119 Free PMC article.
Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells.
Feng J, Pucella JN, Jang G, Alcántara-Hernández M, Upadhaya S, Adams NM, Khodadadi-Jamayran A, Lau CM, Stoeckius M, Hao S, Smibert P, Tsirigos A, Idoyaga J, Reizis B. Feng J, et al. Among authors: smibert p. Immunity. 2022 Mar 8;55(3):405-422.e11. doi: 10.1016/j.immuni.2022.01.016. Epub 2022 Feb 17. Immunity. 2022. PMID: 35180378 Free PMC article.
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE. Morris JA, et al. Among authors: smibert p. Science. 2023 May 19;380(6646):eadh7699. doi: 10.1126/science.adh7699. Epub 2023 May 19. Science. 2023. PMID: 37141313 Free PMC article.
49 results