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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC); Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. Pardiñas AF, et al. Among authors: smart se. JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001/jamapsychiatry.2021.3799. JAMA Psychiatry. 2022. PMID: 35019943 Free PMC article.
Using a statistical learning approach to identify sociodemographic and clinical predictors of response to clozapine.
Fonseca de Freitas D, Kadra-Scalzo G, Agbedjro D, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, MacCabe JH, Hayes RD. Fonseca de Freitas D, et al. Among authors: smart se. J Psychopharmacol. 2022 Apr;36(4):498-506. doi: 10.1177/02698811221078746. Epub 2022 Feb 25. J Psychopharmacol. 2022. PMID: 35212240 Free PMC article.
A predictor model of treatment resistance in schizophrenia using data from electronic health records.
Kadra-Scalzo G, Fonseca de Freitas D, Agbedjro D, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Morris A, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, Hayes RD, MacCabe JH. Kadra-Scalzo G, et al. Among authors: smart se. PLoS One. 2022 Sep 19;17(9):e0274864. doi: 10.1371/journal.pone.0274864. eCollection 2022. PLoS One. 2022. PMID: 36121864 Free PMC article.
Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis.
Pistis G, Vázquez-Bourgon J, Fournier M, Jenni R, Cleusix M, Papiol S, Smart SE, Pardiñas AF, Walters JTR, MacCabe JH, Kutalik Z, Conus P, Crespo-Facorro B, Q Do K. Pistis G, et al. Among authors: smart se. Mol Psychiatry. 2022 Dec;27(12):5135-5143. doi: 10.1038/s41380-022-01779-1. Epub 2022 Sep 21. Mol Psychiatry. 2022. PMID: 36131045 Free PMC article.
Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium.
Smart SE, Agbedjro D, Pardiñas AF, Ajnakina O, Alameda L, Andreassen OA, Barnes TRE, Berardi D, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Di Forti M, Do K, Doody G, Eap CB, Ferchiou A, Guidi L, Homman L, Jenni R, Joyce E, Kassoumeri L, Lastrina O, Melle I, Morgan C, O'Neill FA, Pignon B, Restellini R, Richard JR, Simonsen C, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J, Murray RM, Walters JTR, Stahl D, MacCabe JH. Smart SE, et al. Schizophr Res. 2022 Dec;250:1-9. doi: 10.1016/j.schres.2022.09.009. Epub 2022 Oct 12. Schizophr Res. 2022. PMID: 36242784 Free PMC article.
Clinical correlates of early onset antipsychotic treatment resistance.
Fonseca de Freitas D, Agbedjro D, Kadra-Scalzo G, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Morris A, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, Hayes RD, MacCabe JH. Fonseca de Freitas D, et al. Among authors: smart se. J Psychopharmacol. 2022 Nov;36(11):1226-1233. doi: 10.1177/02698811221132537. Epub 2022 Oct 21. J Psychopharmacol. 2022. PMID: 36268751 Free PMC article.
33 results