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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Andersen OM, Bøgh N, Landau AM, Pløen GG, Jensen AMG, Monti G, Ulhøi BP, Nyengaard JR, Jacobsen KR, Jørgensen MM, Holm IE, Kristensen ML, Alstrup AKO, Hansen ESS, Teunissen CE, Breidenbach L, Droescher M, Liu Y, Pedersen HS, Callesen H, Luo Y, Bolund L, Brooks DJ, Laustsen C, Small SA, Mikkelsen LF, Sørensen CB. Andersen OM, et al. Among authors: small sa. Cell Rep Med. 2022 Sep 20;3(9):100740. doi: 10.1016/j.xcrm.2022.100740. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099918 Free PMC article.
Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease.
Mayeux R, Tang MX, Jacobs DM, Manly J, Bell K, Merchant C, Small SA, Stern Y, Wisniewski HM, Mehta PD. Mayeux R, et al. Among authors: small sa. Ann Neurol. 1999 Sep;46(3):412-6. doi: 10.1002/1531-8249(199909)46:3<412::aid-ana19>3.0.co;2-a. Ann Neurol. 1999. PMID: 10482274
Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.
Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS, Ganetzky B, Duff K, Arancio O, Small SA. Muhammad A, et al. Among authors: small sa. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7327-32. doi: 10.1073/pnas.0802545105. Epub 2008 May 14. Proc Natl Acad Sci U S A. 2008. PMID: 18480253 Free PMC article.
Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling.
Simoes S, Guo J, Buitrago L, Qureshi YH, Feng X, Kothiya M, Cortes E, Patel V, Kannan S, Kim YH, Chang KT; Alzheimer's Disease Neuroimaging Initiative; Hussaini SA, Moreno H, Di Paolo G, Andersen OM, Small SA. Simoes S, et al. Among authors: small sa. Cell Rep. 2021 Dec 28;37(13):110182. doi: 10.1016/j.celrep.2021.110182. Cell Rep. 2021. PMID: 34965419 Free PMC article.
190 results