Small DS - Search Results

1

The Rationale for and Clinical Pharmacology of Prasugrel 5 mg.

Jakubowski JA, Erlinge D, Alexopoulos D, Small DS, Winters KJ, Gurbel PA, Angiolillo DJ. Jakubowski JA, et al. Among authors: small ds. Am J Cardiovasc Drugs. 2017 Apr;17(2):109-121. doi: 10.1007/s40256-016-0202-3. Am J Cardiovasc Drugs. 2017. PMID: 27854064 Review.

2

Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently.

Farid NA, Payne CD, Small DS, Winters KJ, Ernest CS 2nd, Brandt JT, Darstein C, Jakubowski JA, Salazar DE. Farid NA, et al. Among authors: small ds. Clin Pharmacol Ther. 2007 May;81(5):735-41. doi: 10.1038/sj.clpt.6100139. Epub 2007 Mar 14. Clin Pharmacol Ther. 2007. PMID: 17361128 Clinical Trial.

3

Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects.

Farid NA, Jakubowski JA, Payne CD, Li YG, Jin Y, Ernest II CS, Winters KJ, Brandt JT, Salazar DE, Small DS. Farid NA, et al. Among authors: small ds. Curr Med Res Opin. 2009 Aug;25(8):1821-9. doi: 10.1185/03007990903018360. Curr Med Res Opin. 2009. PMID: 19530977 Clinical Trial.

4

Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease.

Small DS, Farid NA, Li YG, Ernest CS 2nd, Winters KJ, Salazar DE, Payne CD. Small DS, et al. J Clin Pharm Ther. 2009 Oct;34(5):575-83. doi: 10.1111/j.1365-2710.2009.01067.x. J Clin Pharm Ther. 2009. PMID: 19744013

5

Inhibition of platelet aggregation with prasugrel and clopidogrel: an integrated analysis in 846 subjects.

Li YG, Ni L, Brandt JT, Small DS, Payne CD, Ernest CS 2nd, Rohatagi S, Farid NA, Jakubowski JA, Winters KJ. Li YG, et al. Among authors: small ds. Platelets. 2009 Aug;20(5):316-27. doi: 10.1080/09537100903046317. Platelets. 2009. PMID: 19637095

6

Effect of age on the pharmacokinetics and pharmacodynamics of prasugrel during multiple dosing: an open-label, single-sequence, clinical trial.

Small DS, Wrishko RE, Ernest CS 2nd, Ni L, Winters KJ, Farid NA, Li YG, Salazar DE, Payne CD. Small DS, et al. Drugs Aging. 2009;26(9):781-90. doi: 10.2165/11315780-000000000-00000. Drugs Aging. 2009. PMID: 19728751 Clinical Trial.

7

The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.

Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, Farid NA, Ni L, Jakubowski JA, Salazar DE, Thieu VT, Payne CD. Small DS, et al. Eur J Clin Pharmacol. 2010 Feb;66(2):127-35. doi: 10.1007/s00228-009-0737-1. Epub 2009 Nov 4. Eur J Clin Pharmacol. 2010. PMID: 19888568 Clinical Trial.

8

Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy Chinese and white volunteers: an open-label trial.

Small DS, Payne CD, Kothare P, Yuen E, Natanegara F, Teng Loh M, Jakubowski JA, Richard Lachno D, Li YG, Winters KJ, Farid NA, Ni L, Salazar DE, Tomlin M, Kelly R. Small DS, et al. Clin Ther. 2010 Feb;32(2):365-79. doi: 10.1016/j.clinthera.2010.02.015. Clin Ther. 2010. PMID: 20206794 Clinical Trial.

9

A comparison of the VerifyNow P2Y12 point-of-care device and light transmission aggregometry to monitor platelet function with prasugrel and clopidogrel: an integrated analysis.

Jakubowski JA, Li YG, Small DS, Payne CD, Tomlin ME, Luo J, Winters KJ. Jakubowski JA, et al. Among authors: small ds. J Cardiovasc Pharmacol. 2010 Jul;56(1):29-37. doi: 10.1097/FJC.0b013e3181dd0ec2. J Cardiovasc Pharmacol. 2010. PMID: 20386460

10

Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent.

Small DS, Li YG, Ernest CS 2nd, April JH, Farid NA, Payne CD, Winters KJ, Rohatagi S, Ni L. Small DS, et al. J Clin Pharmacol. 2011 Mar;51(3):321-32. doi: 10.1177/0091270010367429. Epub 2010 Apr 21. J Clin Pharmacol. 2011. PMID: 20410452 Clinical Trial.

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