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499 results

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RNA N6 -methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer.
Tan B, Zhou K, Liu W, Prince E, Qing Y, Li Y, Han L, Qin X, Su R, Pokharel SP, Yang L, Zhao Z, Shen C, Li W, Chen Z, Zhang Z, Deng X, Small A, Wang K, Leung K, Chen CW, Shen B, Chen J. Tan B, et al. Among authors: small a. Theranostics. 2022 Jul 18;12(13):5727-5743. doi: 10.7150/thno.71872. eCollection 2022. Theranostics. 2022. PMID: 35966596 Free PMC article.
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism.
Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel SP, Gao M, Chen M, Shen C, Tan B, Small A, Wang K, Zhang Z, Qin X, Yang L, Wunderlich M, Zhang B, Mulloy JC, Marcucci G, Chen CW, Wei M, Su R, Chen J, Deng X. Han L, et al. Among authors: small a. Cell Stem Cell. 2023 Jan 5;30(1):52-68.e13. doi: 10.1016/j.stem.2022.12.006. Cell Stem Cell. 2023. PMID: 36608679 Free PMC article.
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia.
Chen Z, Zhou K, Xue J, Small A, Xiao G, Nguyen LXT, Zhang Z, Prince E, Weng H, Huang H, Zhao Z, Qing Y, Shen C, Li W, Han L, Tan B, Su R, Qin H, Li Y, Wu D, Gu Z, Ngo VN, He X, Chao J, Leung K, Wang K, Dong L, Qin X, Cai Z, Sheng Y, Chen Y, Wu X, Zhang B, Shi Y, Marcucci G, Qian Z, Xu M, Müschen M, Chen J, Deng X. Chen Z, et al. Among authors: small a. Sci Transl Med. 2023 Mar 29;15(689):eabq8513. doi: 10.1126/scitranslmed.abq8513. Epub 2023 Mar 29. Sci Transl Med. 2023. PMID: 36989375
RNA m6A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression.
Zhang Z, Zhou K, Han L, Small A, Xue J, Huang H, Weng H, Su R, Tan B, Shen C, Li W, Zhao Z, Qing Y, Qin X, Wang K, Leung K, Boldin M, Chen CW, Ann D, Qian Z, Deng X, Chen J, Chen Z. Zhang Z, et al. Among authors: small a. Genes Dis. 2023 Mar 28;11(1):382-396. doi: 10.1016/j.gendis.2023.01.016. eCollection 2024 Jan. Genes Dis. 2023. PMID: 37588203 Free PMC article.
IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation.
Hong LE, Wechalekar MD, Kutyna M, Small A, Lim K, Thompson-Peach C, Li JJ, Chhetri R, Scott HS, Brown A, Hahn CN, Yeung DT, Sajid S, Robinson N, Thomas R, Branford S, D'Andrea RJ, Samaraweera SE, Patnaik M, Proudman S, Thomas D, Kok CH, Shah MV, Hiwase DK. Hong LE, et al. Among authors: small a. Blood. 2024 May 2;143(18):1873-1877. doi: 10.1182/blood.2023023593. Blood. 2024. PMID: 38457663 Free article.
Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis.
Small AM, Melloni GEM, Kamanu FK, Bergmark BA, Bonaca MP, O'Donoghue ML, Giugliano RP, Scirica BM, Bhatt D, Antman EM, Raz I, Wiviott SD, Truong B, Wilson PWF, Cho K, O'Donnell CJ, Braunwald E, Lubitz SA, Ellinor P, Peloso GM, Ruff CT, Sabatine MS, Natarajan P, Marston NA. Small AM, et al. JAMA Cardiol. 2024 Apr 1;9(4):357-366. doi: 10.1001/jamacardio.2024.0011. JAMA Cardiol. 2024. PMID: 38416462 Clinical Trial.
499 results