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Neutral sphingomyelinase 2 is required for HIV-1 maturation.
Waheed AA, Zhu Y, Agostino E, Naing L, Hikichi Y, Soheilian F, Yoo SW, Song Y, Zhang P, Slusher BS, Haughey NJ, Freed EO. Waheed AA, et al. Among authors: slusher bs. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2219475120. doi: 10.1073/pnas.2219475120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406093 Free PMC article.
Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.
Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Figuera-Losada M, et al. Among authors: slusher bs. PLoS One. 2015 May 26;10(5):e0124481. doi: 10.1371/journal.pone.0124481. eCollection 2015. PLoS One. 2015. PMID: 26010541 Free PMC article.
The Psychiatric Impact of HIV.
Nedelcovych MT, Manning AA, Semenova S, Gamaldo C, Haughey NJ, Slusher BS. Nedelcovych MT, et al. Among authors: slusher bs. ACS Chem Neurosci. 2017 Jul 19;8(7):1432-1434. doi: 10.1021/acschemneuro.7b00169. Epub 2017 May 24. ACS Chem Neurosci. 2017. PMID: 28537385 Free PMC article.
Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.
Nedelcovych MT, Gadiano AJ, Wu Y, Manning AA, Thomas AG, Khuder SS, Yoo SW, Xu J, McArthur JC, Haughey NJ, Volsky DJ, Rais R, Slusher BS. Nedelcovych MT, et al. Among authors: slusher bs. ACS Chem Neurosci. 2018 Apr 18;9(4):809-816. doi: 10.1021/acschemneuro.7b00434. Epub 2018 Jan 4. ACS Chem Neurosci. 2018. PMID: 29257872 Free PMC article.
DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.
Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS. Rojas C, et al. Among authors: slusher bs. Sci Rep. 2018 Dec 7;8(1):17715. doi: 10.1038/s41598-018-36144-2. Sci Rep. 2018. PMID: 30531925 Free PMC article.
Inhibition of neutral sphingomyelinase 2 promotes remyelination.
Yoo SW, Agarwal A, Smith MD, Khuder SS, Baxi EG, Thomas AG, Rojas C, Moniruzzaman M, Slusher BS, Bergles DE, Calabresi PA, Haughey NJ. Yoo SW, et al. Among authors: slusher bs. Sci Adv. 2020 Oct 2;6(40):eaba5210. doi: 10.1126/sciadv.aba5210. Print 2020 Oct. Sci Adv. 2020. PMID: 33008902 Free PMC article.
Astrocytes deliver CK1 to neurons via extracellular vesicles in response to inflammation promoting the translation and amyloidogenic processing of APP.
Li Z, Moniruzzaman M, Dastgheyb RM, Yoo SW, Wang M, Hao H, Liu J, Casaccia P, Nogueras-Ortiz C, Kapogiannis D, Slusher BS, Haughey NJ. Li Z, et al. Among authors: slusher bs. J Extracell Vesicles. 2020 Dec;10(2):e12035. doi: 10.1002/jev2.12035. Epub 2020 Dec 31. J Extracell Vesicles. 2020. PMID: 33408815 Free PMC article.
267 results