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SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes.
Mason AG, Slieker RC, Balog J, Lemmers RJLF, Wong CJ, Yao Z, Lim JW, Filippova GN, Ne E, Tawil R, Heijmans BT, Tapscott SJ, van der Maarel SM. Mason AG, et al. Among authors: slieker rc. Skelet Muscle. 2017 Jun 6;7(1):12. doi: 10.1186/s13395-017-0129-7. Skelet Muscle. 2017. PMID: 28587678 Free PMC article.
Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells.
Bomer N, den Hollander W, Suchiman H, Houtman E, Slieker RC, Heijmans BT, Slagboom PE, Nelissen RG, Ramos YF, Meulenbelt I. Bomer N, et al. Among authors: slieker rc. Osteoarthritis Cartilage. 2016 Aug;24(8):1423-30. doi: 10.1016/j.joca.2016.03.009. Epub 2016 Mar 17. Osteoarthritis Cartilage. 2016. PMID: 26995110 Free article.
DNA Methylation Landscapes of Human Fetal Development.
Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM. Slieker RC, et al. PLoS Genet. 2015 Oct 22;11(10):e1005583. doi: 10.1371/journal.pgen.1005583. eCollection 2015 Oct. PLoS Genet. 2015. PMID: 26492326 Free PMC article.
Blood lipids influence DNA methylation in circulating cells.
Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, Mei H, Zhernakova DV, van den Berg LH, Deelen J, van Dongen J, van Heemst D, Hofman A, Hottenga JJ, van der Kallen CJ, Schalkwijk CG, Stehouwer CD, Tigchelaar EF, Uitterlinden AG, Willemsen G, Zhernakova A, Franke L, 't Hoen PA, Jansen R, van Meurs J, Boomsma DI, van Duijn CM, van Greevenbroek MM, Veldink JH, Wijmenga C; BIOS Consortium; van Zwet EW, Slagboom PE, Jukema JW, Heijmans BT. Dekkers KF, et al. Among authors: slieker rc. Genome Biol. 2016 Jun 27;17(1):138. doi: 10.1186/s13059-016-1000-6. Genome Biol. 2016. PMID: 27350042 Free PMC article.
Disease variants alter transcription factor levels and methylation of their binding sites.
Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium; Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT. Bonder MJ, et al. Among authors: slieker rc. Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5. Nat Genet. 2017. PMID: 27918535
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.
Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM. Roost MS, et al. Among authors: slieker rc. Nat Commun. 2017 Oct 13;8(1):908. doi: 10.1038/s41467-017-01077-3. Nat Commun. 2017. PMID: 29030611 Free PMC article.
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array.
Slieker RC, Bos SD, Goeman JJ, Bovée JV, Talens RP, van der Breggen R, Suchiman HE, Lameijer EW, Putter H, van den Akker EB, Zhang Y, Jukema JW, Slagboom PE, Meulenbelt I, Heijmans BT. Slieker RC, et al. Epigenetics Chromatin. 2013 Aug 6;6(1):26. doi: 10.1186/1756-8935-6-26. Epigenetics Chromatin. 2013. PMID: 23919675 Free PMC article.
78 results